Search for dissertations about: "oxidative stress genes"

Showing result 1 - 5 of 106 swedish dissertations containing the words oxidative stress genes.

  1. 1. The oxidative stress response of Francisella tularensis

    Author : Marie Honn; Anders Sjöstedt; Helena Lindgren; Andres Melendez; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; FupA; MglA; OxyR; ROS; oxidative stress; molekylärbiologi; Molecular Biology;

    Abstract : Francisella tularensis is capable of infecting numerous cell types, including professional phagocytes. Upon phagocytosis, F. tularensis resides within the phagosome before escaping into the cytosol to replicate. Phagocytes constitute a hostile environment rich in ROS, which are employed as a means of killing pathogens. READ MORE

  2. 2. Susceptibility genes in conformational diseases

    Author : Malin von Otter; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Conformational disease; Alzheimer’s disease; Parkinson’s disease; Cataract Protein aggregation; Cellular transport; Oxidative stress; Susceptibility; genes; SNP; Haplotype;

    Abstract : Conformational diseases are characterized by protein misfolding and aggregation in the affected tissue. The aim of this thesis was to find genetic support for mechanisms in common for three prevalent ... READ MORE

  3. 3. Role of oxidative stress response in radiosensitivity

    Author : Ali Pour Khavari; Siamak Haghdoost; Bo Stenerlöw; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Oxidative stress; radiosensitivity; 8-oxo-dG; DNA-repair; NRF2; glioblastoma; radiotherapy; molekylär biovetenskap; Molecular Bioscience;

    Abstract : The quality of the ionizing radiation (IR) can be described in terms of its nature, photons or particles, and their corresponding energies. The energy is classified in terms of High or Low linear energy transfer that will produce a different distribution of DNA damage and other molecules in the cell either by direct action or indirect action. READ MORE

  4. 4. Biotic and abiotic stress in microorganisms and plants: Some Mechanisms of Stress and Programmed Cell Death. Genetic Engineering Approaches Towards Improved Stress Tolerance

    Author : Per-Johan Meijer; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; biotic stress; plants; microorganisms; stress tolerance; antifreeze protein; proline; programmed cell death; systemic aquired resistance; Biochemistry; metabolism; Biokemi; Bioteknik; Biotechnology; abiotic stress;

    Abstract : Various forms of stress, such as biotic and abiotic stress, were studied in microorganisms and plants to learn more about the underlying mechanisms of such stress and potential genetic engineering strategies towards stress tolerance. An antifreeze protein from winter flounder, expressed in E. READ MORE

  5. 5. Oxidative stress and alterations in the mammalian iron metabolism : A study on iron, inflammation, oxidative stress and neurodegeneration

    Author : Jonas Hälldin; Tiit Land; Paolo Arosio; Stockholms universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry; Neurokemi; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Abstract : Iron is essential for all living organisms, from bacteria to man for a broad variety of biological functions, including oxygen transport and DNA synthesis. However, iron can also be toxic, due to its involvement in the formation of highly reactive oxygen species through Fenton chemistry. READ MORE