Search for dissertations about: "oxidative stress genes"

Showing result 6 - 10 of 124 swedish dissertations containing the words oxidative stress genes.

2. 6. Molecular genetic studies of oxidative stress related genes

   Author : Louise Lyrenäs; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Gene regulation; oxidative stress; genetic variation; catalase; MGST1; PGES;

   Abstract : This work has focused on the basal characterisation of transcriptional regulation, including genetic variants, in oxidative stress related genes and the possible impact of such variation in cardiovascular disease. The genes under study were catalase and MGST1/PGES where the two former protect from hydrogen peroxide and lipid hydroperoxides respectively and the latter is important in e. READ MORE

4. 7. Coordination of two different genomes in response to light and stress

   Author : Louise Norén Lindbäck; Åsa Strand; Antony Dodd; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Arabidopsis thaliana; chloroplast; cellular communication; tetrapyrrole; circadian clock; oxidative stress; light signalling; gene regulation; molekylärbiologi; Molecular Biology;

   Abstract : About 1.5 billion years ago, a photosynthetic bacteria was engulfed by a eukaryotic cell which initiated a symbiotic relationship and the evolution of the chloroplast as we know it today. The chloroplast has retained its own genome encoding for a number of proteins required for the function of the chloroplast. READ MORE

5. 8. Oxidative stress-related factors in abdominal aortic aneurysm: potential clinical implications

   Author : Sakshi Vats; Allmänmedicin och klinisk epidemiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; abdominal aortic aneurysm AAA ; mitochondria; Heme; Oxidative stress; Genetics; Epigenetic;

   Abstract : Abdominal aortic aneurysm (AAA) is a mostly silent vascular disease, with a rupture-related mortality rate exceeding 80%. To aid in future diagnosis and prognosis efforts, the studies included in the present thesis have explored the role of specific oxidative stress-related factors in the context of AAA using two population-based cohorts: AAA screening cohort of 65-year-old males (n = 421) and the Malmö diet and cancer study (MDCS) (n = 25252). READ MORE

6. 9. Factors influencing the risk of diabetic nephropathy : analyses of genes, smoking and diet

   Author : Anna Möllsten; Gisela Dahlquist; Lise Tarnow; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1 diabetes; diabetic nephropathy; oxidative stress; smoking; diet; blood pressure; renin-angiotensin system; nitric oxide synthase; Kidney diseases; Njursjukdomar;

   Abstract : Diabetic long-term complications, despite intensive treatment, cause serious handicaps at relatively young age in diabetic patients. Diabetic nephropathy (DN) develops in up to 30% of patients with type 1 diabetes (T1D). READ MORE

7. 10. Genetic variation and regulation of oxidative stress related genes

   Author : Lena Forsberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Oxidative stress, is a state that has been implicated in the pathogenesis of a variety of human diseases, including atherosclerosis, inflammation, neurodegenerative disease and cancer. In an effort to determine the importance of oxidative stress in disease etiology, by a genetic approach, we have, studied individual variation and regulation of oxidative stress related genes including also basal characterization. READ MORE