Search for dissertations about: "oxidative stress surgery"

Showing result 1 - 5 of 24 swedish dissertations containing the words oxidative stress surgery.

2. 1. Influence of Oxidative Stress on Muscle and Bone

   Author : Bengt Östman; Karl Michaëlsson; Lars Nordsletten; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone mineral density; coenzyme Q10; exercise; ischaemia; isprostanes; muscle; oxidative stress; oxygen radicals; reperfusion; tocopherol; Orthopaedics; Ortopedi; ortopedi; Orthopaedics;

   Abstract : Reactive oxygen species (ROS) induce oxidative stress and although are primarily recognized for playing a deleterious biological role, they can be beneficial to cell systems. ROS are extremely short-lived and normally tightly regulated by antioxidant defence systems. READ MORE

4. 2. Experimental cardiopulmonary cerebral resuscitation : A study of cerebral perfusion with special reference to the postresuscitation disturbances

   Author : Ala Nozari; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Cardiac arrest; cardiopulmonary resuscitation; cerebral blood flow; post-resuscitation period; epinephrine; vasopressin; aortic occlusion; isoprostane; Kirurgi; Surgery; Kirurgi; Anestesiologi; Anaesthesiology;

   Abstract : Ischemic neuronal injury continues to be a major delimiting factor in achieving successful clinical outcomesafter resuscitation from cardiac arrest. In this thesis, a pig model of cardiopulmonary resuscitation (CPR) wasused to address the effects of different interventions on cerebral blood flow and oxygenation during CPR and theinitial postresuscitation period. READ MORE

5. 3. Experimental studies on thrombosis and thrombolysis : With special reference to importance of lys-plasminogen, active site thrombin inhibitors and stable fish oil

   Author : Liying Chen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Thrombolysis; thrombosis; recombinant tissue-type plasminogen activator; lys- and glu-plasminogen; aspirin; thrombin inhibitors; platelets; superoxide dismutase; stable fish oil; Kirurgi; Surgery; Kirurgi; rättsmedicin; Forensic Medicine;

   Abstract : Dissolution and prevention of thrombus in the atherosclerotic coronary artery have become an important part of treatment therapy of acute myocardial infarction. However, the currently most effective thrombolytic agent, recombinant tissue-type plasminogen activator (rt-PA), only elicits 80% recanalization of thrombotically occluded coronary arteries and early occlusion occurs in about 40% of successfullyrecanalized vessels. READ MORE

6. 4. Nitric oxide : An ally in extracorporeal circulation?

   Author : Vilyam Melki; Jan Borowiec; Örjan Friberg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Simulated extracorporeal circulation; Inflammation; Nitric oxide; Leukocyte activation; Staphylococcus aureus; Glyceryl trinitrate; Postoperative infection; Thorax Surgery; Thoraxkirurgi;

   Abstract : Many complications associated with heart surgery are due to the negative effects of extracorporeal circulation (ECC). Some of these complications may be attributed to ECC-induced activation of inflammation and coagulation pathways. READ MORE

7. 5. Mechanisms and improvements of cell transplantation for nerve repair

   Author : Kai-Hei Tse; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stem cells; microporous scaffold; biomaterials; ischemia; cell death; brain derived neurotrophic factor;

   Abstract : Trauma to the nervous system is a frequent clinical problem and new approaches to nerve repair are required. Autologous cell transplantation together with a suitable scaffold material could be used to create a bio-active artificial nerve graft to enhance regeneration. READ MORE