Search for dissertations about: "oxidized lipids"

Showing result 6 - 10 of 30 swedish dissertations containing the words oxidized lipids.

  2. 6. Regulation of human macrophage gene expression by oxidized low density lipoprotein. Studies on tumor necrosis factor-a and global gene expression profiles

    Author : Mikael C. O. Englund; Göteborgs universitet; []
    Keywords : atherosclerosis; macrophage; gene expression; TNF-a; oxidized LDL; oxysterol; transcription factor; microarray;

    Abstract : Atherosclerosis is a multifactorial and progressive disease that is characterized by a focal thickening of the arteries caused by accumulation of lipoproteins, extracellular matrix, and the migration and proliferation of various cell types. Among the cells found in atherosclerotic lesions are macrophages, which accumulate lipids and are transformed into foam cells. READ MORE

  4. 7. Lipids and autoimmunity in atherosclerosis and cardiovascular diseases

    Author : Xiang Hua; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Atherosclerosis is an inflammatory disease. The rupture of athrerosclerotic plaques is the major cause of severe cardiovascular disease (CVD), such as myocardial infarction (MI) and stroke. The stability of the plaque depends on its cellular and extracellular contents. READ MORE

  5. 8. Intracellular lipids and inflammatory activity in macrophage foam cells

    Author : Jenny Persson; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; lipid droplet; cytokine; inflammation; adipophilin; perilipin; atherosclerosis; Macrophage; foam cell;

    Abstract : Cardiovascular disease (CVD) is characterized by lipid accumulation and inflammation in arteries. The disease starts early in life with migration of monocytes into the arterial wall where they engulf entrapped lipoproteins and become macrophage foam cell. READ MORE

  6. 9. Development of a Passive Immunization Strategy Against Atherosclerosis

    Author : Alexandru Schiopu; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; regression; plaque; peptide; oxidized LDL; immune system; carotid stenosis; cardiovascular diseases; apolipoprotein B-100; atherosclerosis; Kardiovaskulära systemet; Cardiovascular system; vascular injury; ultrasound; antibodies;

    Abstract : Atherosclerosis is a chronic inflammatory disease, characterized by the accumulation of lipids and fibrous tissue in the wall of medium and large-sized arteries. The characteristic culprit of the disease is the atheroma, or atherosclerotic plaque, a patchy thickening of the arterial wall which affects the lumen, inducing various degrees of stenosis. READ MORE

  7. 10. Compositional clues to sources and sinks of terrestrial organic matter transported to the Eurasian Arctic shelf

    Author : Emma Karlsson; Örjan Gustafsson; Volker Brüchert; Thorsten Dittmar; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; organic carbon; degradation; microcosm; incubation; terrestrial biomarkers; acyl lipids; lignin phenols; radiocarbon; Eurasian Arctic shelf; East Siberian Sea; Laptev Sea; Lena River; colloidal matter; particulate matter; sedimentary matter; Applied Environmental Science; tillämpad miljövetenskap;

    Abstract : The amount of organic carbon (OC) present in Siberian Arctic permafrost soils is estimated at twice the amount of carbon currently in the atmosphere. The shelf seas of the Arctic Ocean receive large amounts of this terrestrial OC from Eurasian Arctic rivers and from coastal erosion. READ MORE