Search for dissertations about: "oxindoles"

Found 3 swedish dissertations containing the word oxindoles.

  2. 1. New Methods for the Synthesis of Vicinal Stereocenters : Palladium-Catalyzed Domino Reactions and Asymmetric Transfer Hydrogenation

    Author : Brinton Seashore-Ludlow; Somfai Peter; Kevin Booker-Milburn; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; asymmetric synthesis; domino reactions; palladium-catalyzed reactions; oxindoles; amino alcohols;

    Abstract : In this thesis the synthesis of vicinal stereocenters is investigated in two distinct contexts, namely the construction of 3,3-disubstituted oxindoles and the synthesis of b-hydroxy-a-amino acids. Both scaffolds are prevalent in a range of natural products and biologically relevant compounds and, therefore, methods for their synthesis are of great import. READ MORE

  4. 2. Development of catalytic enantioselective C-C bond-forming and cascade transformations by merging homogeneous or heterogeneous transition metal catalysis with asymmetric aminocatalysis

    Author : Samson Afewerki; Armando Córdova; MICHELANGELO GRUTTADAURIA; Mittuniversitetet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; asymmetric catalysis; transition metals; aldehydes; heterogeneous catalysis; amino acid; organocatalysis; α-allylation; β-alkylation; dynamic transformations; polysubstituted; carbocycles; spirocyclic oxindoles; all-carbon quaternary stereocenters;

    Abstract : Chiral molecules play a central role in our daily life and in nature, for instance the different enantiomers or diastereomers of a chiral molecule may show completely different biological activity. For this reason, it is a vital goal for synthetic chemists to design selective and efficient methodologies that allow the synthesis of the desired enantiomer. READ MORE

  5. 3. Synthesis of indoles, bisindoles and indolocarbazoles : high affinity aryl hydrocarbon receptor ligands

    Author : Niklas Wahlström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Indole; bisindoles; carbazole; indolocarbazole; indolo[3; 2-b]carbazole; ICZ; FICZ; alkaloid; metabolite; tropolone; caulersin; aryl hydrocarbon receptor; Ali receptor; X-ray crystallography; Lewis acid; acylation; Vilsmeier reaction.;

    Abstract : This thesis deals with the synthesis and reactions of indoles, bisindoles, indolocarbazoles and their derivatives. New methods for ring formation of planar, heterocyclic quinones, with the indolo[3,2b]carbazole or indolo[2,3-b]carbazole structures are described. READ MORE