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Showing result 1 - 5 of 22 swedish dissertations matching the above criteria.
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1. Mechanisms of P fimbriae cell activation
Abstract : Microbial attachment to host cells plays a central role in the induction of inflammatory responses and the production of the disease. Uropathogenic Gram negative bacteria carry surface lectins that specifically recognize oligosaccharide receptor epitopes expressed on glycolipids or glycoproteins. READ MORE
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2. Febrile Urinary Tract Infection: P fimbriae, Innate Host Response and Bacteremia
Abstract : Urinary tract infections (UTI) are among the most common human infections, and febrile UTI with bacteremia the most severe form. The relation between bacteria and host decides disease severity. The dominating uropathogen is Escherichia coli (E. coli). READ MORE
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3. Escherichia coli Fimbriae, Bacterial Persistence and Host Response Induction in the Human Urinary Tract
Abstract : Urinary tract infections (UTI) are among the most common bacterial infections in humans. Symptomatic UTIs may be acute, recurrent or chronic but the most frequent form of UTI is asymptomatic bacteruria (ABU). In ABU, the mucosa remains inert, despite the presence of large bacterial numbers in urine. READ MORE
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4. The role of P fimbriae for Escherichia coli establishment and mucosal inflammation in the human urinary tract
Abstract : Bacterial adhesion to the bladder mucosa is a critical step for the establishment of Escherichia coli bacteriuria. The P-fimbriae, encoded by the pap gene cluster, are considered as virulence factors but the mechanisms have been debated. This study defined the roles for P fimbriation during the early colonization of the human urinary tract. READ MORE
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5. Molecular determinants of disease severity in urinary tract infection
Abstract : In the urinary tract, Escherichia coli infection may result in life-threatening disease, or asymptomatic bacterial carriage, comparable to bacterial commensalism in the gut. Pathogenic strains trigger a disease provoking host response which differs depending on the infected organ. READ MORE