Search for dissertations about: "p38"

Showing result 21 - 25 of 133 swedish dissertations containing the word p38.

  2. 21. Properties of Endothelium and its Importance in Endogenous and Transplanted Islets of Langerhans

    Author : Åsa Johansson; Per-Ola Carlsson; JanOve Sehlin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; islet transplantation; endothelial cells; engraftment; beta cells; Diabetology; Diabetologi; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Transplantation of insulin producing cells is currently the only cure for type 1 diabetes. However, even though the Edmonton protocol markedly increased the success rate of pancreatic islet transplantation, the long term insulin independence is still very poor. An adequate engraftment is critical for islet graft survival and function. READ MORE

  4. 22. On Neutrophil and Platelet Adhesive Interactions in Septic Lung Injury

    Author : Asad Muhammad; Kirurgi; []
    Keywords : Leukocytes; chemokines; platelets; lung; sepsis;

    Abstract : Sepsis induced by intestinal perforation is a life-threatening illness and is a frequent cause of leukocyte-mediated lung injury. Although antimicrobial therapy has been the central clinical strategy for these patients, the survival rates in such patients are still very low because of their impaired host defense mechanisms. READ MORE

  5. 23. On Microvascular Inflammation and Intestinal Leakage in Radiation Enteropathy

    Author : Andrada Röme; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiation; colon; intestinal leakage; Leukocyte and platelet recruitment;

    Abstract : Gastrointestinal tract damage is an insidious feature in patients undergoing radiotherapy. Microvascular inflammation, including leukocyte and platelet recruitment as well as epithelial barrier dysfunction, are considered to constitute key components in the pathophysiology of radiation-induced enteropathy. READ MORE

  6. 24. Changes in mitogen-activated protein kinase phosphorylation and inorganic phosphate induced by skeletal muscle contraction

    Author : Charlott Wretman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Skeletal muscle; MAP kinase; signal transduction; contraction; acute exercise; exercise intensity; fibre-type; concentric; ROS; eccentric.;

    Abstract : Skeletal muscles adjust to the level of contractile activity by different biochemical alterations. Contraction is a multifactorial stimulus with short-term metabolic effects and long-term responses due to changes in protein synthesis. READ MORE

  7. 25. The role of glucocorticoid receptors and mitogen-regulated protein kinases in the cochlea

    Author : Inna Meltser; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hearing loss induced by acoustic trauma is a common handicap for the human population. Acoustic trauma triggers a cascade of changes in the cochlea such as a direct mechanical damage of sensory hair cells, biochemical disturbances including reactive oxygen and nitrogen species generation, release of pro-inflammatory cytokines and exitotoxicity. READ MORE