Search for dissertations about: "p53 gene"
Showing result 1 - 5 of 208 swedish dissertations containing the words p53 gene.
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1. Radiosensitivity in lung cancer with focus on p53
Abstract : In Sweden approximately 2800 new lung cancer patients are diagnosed every year. Radiotherapy is used with curative intention in certain groups of patients. The aim of this thesis is to study the basis of differences in radioresistance and the possibility to predict response to radiotherapy. READ MORE
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2. Microarray Based Gene Expression Analysis in Cancer Research
Abstract : Biotechnological inventions during the 20th century have resulted in a wide range of approaches for explorations in the functional genomics field. Microarray technology is one of the recent advances which have provided us with snapshots of which genes are expressed in cells of various tissues and diseases. READ MORE
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3. p53 Alterations in Human Skin : A Molecular Study Based on Morphology
Abstract : Mutation of the p53 gene appears to be an early event in skin cancer development. The present study is based on morphology and represents a cellular and genetic investigation of p53 alterations in normal human skin and basal cell cancer. READ MORE
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4. On the function of the interferon-inducible p53 target gene TRIM22
Abstract : The interferon-inducible p53-target gene TRIM22 (Staf50) is a member of the TRIM (TRIpartite Motif) family. The TRIM family is a family of RING (Really Interesting New Gene) proteins, defined through a tripartite motif, containing a RING-domain, one or two B-boxes and a Coiled-coil-domain. READ MORE
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5. Optimizing experimental radioimmunotherapy : investigating the different mechanisms behind radiation induced cell deaths
Abstract : Background. Radiation therapy is an important treatment regimen for malignant disease. Radiation therapy uses ionizing radiation to induce DNA damage in tumor cells in order to kill them. READ MORE