Search for dissertations about: "pH gating"

Showing result 1 - 5 of 12 swedish dissertations containing the words pH gating.

  2. 1. Structural transitions of proton-gated ion channels : Involving pH sensing, heterogeneity and lipid interactions

    Author : Urška Rovšnik; Erik Lindahl; Hugues Nury; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ion channels; cryo-electron microscopy; pH gating; simulations; structure-function relationship; GLIC; DeCLIC; biokemi; Biochemistry;

    Abstract : Studying protein structure and function involves analyzing the relationship between a protein's three-dimensional assembly and its dynamic biochemical activity. The superfamily of pentameric ligand-gated ion channels (pLGICs) constitutes a classic yet illuminating experimental system for structure-function studies. READ MORE

  4. 2. Interpolymer complexation of a polymer brush

    Author : John Andersson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; functional materials; macromolecular gating; Interpolymer complex; nanopores; polymer brush; pH responsive;

    Abstract : Controllable macromolecular gating between nanoscopic compartments is of high interest for single molecule studies of biological macromolecules. By definition, a good macromolecular gate should completely stop biomolecules, such as proteins, from crossing between compartments in its closed state while letting them pass in its open state. READ MORE

  5. 3. Plant aquaporin regulation: Structural and functional studies using diffraction and scattering techniques

    Author : Michael Järvå; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; X-ray Crystallography; Membrane protein; Plasma membrane intrinsic protein; Aquaporin; pH gating; mercury; proteoliposome assay; water transport; SANS; SAXS; WAXS; nanodisc; liposome;

    Abstract : Water is the basis for life as we know it. It is only logical then that all organisms have evolved specialized proteins, aquaporins, which regulate water flow across their membranes. Plants, which are immobile, depend more on their environment and also use water flows to move, to breathe, and to grow. READ MORE

  6. 4. Functional polymer brush coatings for nanoscale devices

    Author : John Andersson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; poly ethylene glycol ; nanopores; electrochemistry; silatranes; func- tional materials; polymer brush; Nanobiotechnology; interpolymer complex; pH re- sponsive; macromolecular gating.;

    Abstract : Nanobiotechnology is an interdisciplinary field that has garnered considerable attention for offering exciting new opportunities of studying and manipulating biomolecules at the nanoscale. This prospect bears large potential benefits in the field of medicine and the whole life science sector in general. READ MORE

  7. 5. Membrane Induced Structure in Transmembrane Signaling Proteins and Peptides : Peptide–Lipid Interactions Studied by Spectroscopic Methods

    Author : Sofia E. Unnerståle; Lena Mäler; Jason Schnell; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; peptide-lipid interaction; paddle domain; voltage gating; voltage sensor domain; micelle; phospholipid bicelle; solution structure; HAMP domain; nuclear magnetic resonance spectroscopy; circular dichroism spectroscopy; nonspecific interaction; Biophysics; biofysik;

    Abstract : Biological membranes, defining the boundary of cells and eukaryotic organelles, are mainly composed of lipids and membrane proteins. Interactions between these lipids and proteins are needed to preserve the tight seal of the membrane, but also to induce structure for proper function in many membrane proteins. READ MORE