Search for dissertations about: "padlock probe"
Showing result 11 - 15 of 27 swedish dissertations containing the words padlock probe.
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11. Detection of Biomolecules Using Volume-Amplified Magnetic Nanobeads
Abstract : This thesis describes a new approach to biomolecular analysis, called the volume-amplified magnetic nanobead detection assay (VAM-DNA). It is a sensitive, specific magnetic bioassay that offers a potential platform for the development of low-cost, easy-to-use diagnostic devices. READ MORE
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12. Single Molecule Detection : Microfluidic Automation and Digital Quantification
Abstract : Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, which now permit the detection and analysis of single molecules with high sensitivity and specificity. Assay sensitivity is fundamentally limited by the efficiency of the detection method used for read-out. READ MORE
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13. Molecular Tools for Biomarker Detection
Abstract : The advance of biological research promotes the emerging of new methods and solutions to answer the biological questions. This thesis describes several new molecular tools and their applications for the detection of genomic and proteomic information with extremely high sensitivity and specificity or simplify such detection procedures without compromising the performance. READ MORE
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14. Ligation-mediated Molecular Analysis of Influenza Subtypes, Splicing and Protein Glycosylation
Abstract : Binder-based assays are employed throughout the life sciences. Powerful signal amplification techniques have enabled detection of very rare molecule species diluted in simple buffers. Unspecific binding of primary binders leads to increased background in more complex samples. READ MORE
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15. Nucleic Acid Based Pathogen Diagnostics
Abstract : Pathogenic organisms are transmitted to the host organism through all possible connected pathways, and cause a myriad of diseases states. Commonly occurring curable infectious diseases still impose the greatest health impacts on a worldwide perspective. READ MORE