Search for dissertations about: "palladium"

Showing result 6 - 10 of 319 swedish dissertations containing the word palladium.

2. 6. Palladium-Catalysed Carbon–Carbon Coupling Reactions : Focusing on Microwave Heating, Low Catalyst Concentrations, Aqueous Conditions, Regioselectivity and Medicinal Chemistry Applications

   Author : Riina K Arvela; Mats Larhed; Anders Hallberg; Michael G Organ; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Suzuki coupling; Heck reaction; palladium; microwave heating; water; vinyl ethregioselective; HIV-1 integrase inhibitor; Pharmaceutical chemistry; Farmaceutisk kemi; farmaceutisk biokemi; Pharmaceutical Biochemistry;

   Abstract : It is widely accepted that palladium is one of the most useful catalysts in organic chemistry, and many palladium(0)-catalysed carbon–carbon bond-forming reactions have been developed over the years. In addition, the ever-growing need for more environmentally benign processes in the chemical industry has driven scientists to look for greener options while developing new methodologies for organic synthesis. READ MORE

4. 7. Ligand Dependent Regioselectivity in Palladium Mediated Allylic Alkylation

   Author : Charlotte Johansson; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Palladium; allylic alkylation; η3-allyl palladium complexes; regioselectivity; PN-ligand; memory effects; dynamics; ligand effect; trans effects.;

   Abstract : In this thesis, different aspects on ligand dependent regioselectivity in palladium mediated allylic alkylation have been studied. It is believed that the regioselectivity is a result of nucleophilic attack trans to phosphorous when applying ligands wih different donor atoms. READ MORE

5. 8. Palladium-Catalyzed Nucleophilic Substitution of Alcohols : Mechanistic Studies and Synthetic Applications

   Author : Supaporn Sawadjoon; Joseph Samec; Takao Ikariya; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; palladium; nucleophilic substitution; mechanism; Organic Chemistry; Organisk kemi;

   Abstract : This thesis deals with the palladium-catalyzed nucleophilic substitution of π-activated alcohols in which the C–O bond of a non-manipulated hydroxyl group is cleaved. The thesis is divided in two chapters describing two different catalytic systems. READ MORE

6. 9. Palladium-Catalysed Couplings in Organic Synthesis : Exploring Catalyst-Presenting Strategies and Medicinal Chemistry Applications

   Author : Alejandro Trejos; Mats Larhed; Jianliang Xiao; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mizoroki-Heck arylation; Suzuki coupling; domino reaction; stereoselective; palladium; chelation control; vinyl ether; HIV-protease inhibitors; HIV-integrase inhibitors; Kemi med inriktning mot organisk kemi; Chemistry with specialization in Organic Chemistry;

   Abstract : Palladium-catalysed coupling reactions have been embraced by synthetic chemists as one of the preferred means for smooth formation of new carbon-carbon bonds: a truly ubiquitous methodology of synthesizing complex molecules.This thesis describes the study of a series of palladium(0)-catalysed C2-arylations of a 1-cyclopentenyl ether, equipped with a chiral (S)-N-methyl-pyrrolidine auxiliary. READ MORE

7. 10. Palladium-Catalyzed Carbonylation and Arylation Reactions

   Author : Jonas Sävmarker; Mats Larhed; Gary Molander; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; palladium; carbonylation; styrene; amidine; aryl ketones; aryl sulfinates; ESI-MS; aryltrifluoroborates; Organic Pharmaceutical Chemistry; Organisk farmaceutisk kemi;

   Abstract : Palladium-catalyzed reactions have found widespread use in contemporary organic chemistry due to their impressive range of functional group tolerance and high chemo- and regioselectivity. The pioneering contributions to the development of the Pd-catalyzed C-C bond forming cross-coupling reaction were rewarded with the Nobel Prize in Chemistry in 2010. READ MORE