Search for dissertations about: "palliative radiotherapy"

Showing result 1 - 5 of 17 swedish dissertations containing the words palliative radiotherapy.

  2. 1. Optimization of radiotherapy in locally advanced lung cancer

    Author : Andreas Hallqvist; Göteborgs universitet; []
    Keywords : radiotherapy; lung cancer;

    Abstract : Lung cancer is the leading cause of cancer death worldwide as well as in Sweden, where the incidence is around 3500 new cases per year. About 50% have distant metastases by the time of diagnosis and are treated with palliative intent. READ MORE

  4. 2. Experimental and population-based studies on colorectal cancer - Thymidine phosphorylase as a potential biomarker

    Author : Elinor Bexe-Lindskog; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; thymidine phosphorylase; chemotherapy; adjuvant; biological markers; prognosis; practice guidelines; radiotherapy;

    Abstract : Background: Colorectal cancer (CRC) is one of the most common malignancies, and the only reliable treatment option for cure is surgery. Method: Quantitative real-time polymerase chain reaction was used to analyze the gene expression of the enzyme thymidine phosphorylase (TP), which was related to prognostic factors (paper I, n=254), evaluated as a predictive factor (paper III, n=125), and assessed by change of treatment (paper II, n=28). READ MORE

  5. 3. Towards improved oncological treatment of esophageal and gastric cancer. Clinical and translational studies

    Author : David Borg; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Esophageal adenocarcinoma; Gastric cancer; PODXL; Prognosis; Prediction; Chemotherapy dose intensity; Dysphagia; Radiotherapy;

    Abstract : BackgroundThe overall aim of this thesis was to improve the oncological treatment strategies in esophageal and gastric adenocarcinoma (EGAC). Podocalyxin-like protein 1 (PODXL) has been associated with poor prognosis in other cancers and we wanted to investigate its potential role as a prognostic and predictive biomarker in resectable EGAC. READ MORE

  6. 4. Rectal Cancer : Surgical Strategies and Histopathological Aspects

    Author : Maziar Hosseinali Khani; Kenneth Smedh; Lars Påhlman; Brendan Moran; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rectal cancer; APR; en bloc resection; CRM; centralization; stage IV; metastases; palliative surgery; local recurrence; survival; Surgery; Kirurgi; Kirurgi; Surgery;

    Abstract : The management of rectal cancer has changed in many countries over the last two decades and resulted in improved survival for the majority of rectal cancer patients. In this thesis some surgical strategies and histopathological aspects to improve and clarify the management of rectal cancer patients are investigated. READ MORE

  7. 5. Aspects of chemotherapy and photon and proton radiotherapy in patients with gastric cancer

    Author : Michael Gubanski; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Gastric cancer remains a major health problem worldwide. The addition of chemotherapy alone or in combination with radiotherapy to surgery in local gastric cancer improves outcome. In more advanced stages, the optimal palliative chemotherapy remains unknown, as well as the effect of different regimens on the patients’ quality of life. READ MORE