Search for dissertations about: "pancreas"

Showing result 1 - 5 of 221 swedish dissertations containing the word pancreas.

  1. 1. Imaging the pancreas new aspects on lobular development and adult constitution

    University dissertation from Umeå : Umeå universitet

    Author : Andreas Hörnblad; Umeå universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; ß-cell mass; tertiary lymphoid organs; biomedical imaging; optical projection tomography; morphogenesis; pancreas development; gastric lobe; spleen development.; medicinsk genetik; Medical Genetics; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences; molekylär medicin genetik och patologi ; Molecular Medicine;

    Abstract : The mouse pancreas is a mixed exocrine and endocrine glandconsisting of three lobular compartments: the splenic, duodenal and gastric lobes. During embryogenesis, the pancreas forms from two progenitor populations located on the dorsal and ventral side of the primitive gut tube. READ MORE

  2. 2. Pancreas Transplantation: Development of Successful Preclinical Models

    University dissertation from Surgery Research Unit

    Author : Wayne John Hawthorne; Lunds universitet.; Lund University.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute rejection; simultaneous pancreas and kidney transplant; portal venous drainage; systemic venous drainage; pancreaticoduodenal transplant; segmental pancreas transplant; duct-occlusion; autograft; Pancreas transplantation; allograft; hyperacute rejection; glucose metabolism.; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Abstract : Pancreas transplantation is today a technically successful procedure and provides an alternative to insulin injections for the treatment of Type I diabetes mellitus. This thesis was undertaken while pancreas transplantation was developing and while several fundamental questions were being asked about both endocrine and exocrine drainage of the transplanted pancreas as well as how best to diagnose and prevent rejection. READ MORE

  3. 3. Immunopathology of the Pancreas in Type 1 Diabetes

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anna Wiberg; Uppsala universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; glucagon; T cells; autoantibodies; glucose transporters; islets of Langerhans; pancreas; Klinisk immunologi; Clinical Immunology;

    Abstract : Type 1 diabetes (T1D) results from a loss of functional insulin-producing pancreatic beta cells. The etiology of T1D is poorly understood, but the detection of infiltrating inflammatory cells in the pancreas and circulating autoantibodies has led to the common notion that an autoimmune process plays a central role in the pathogenesis of the disease. READ MORE

  4. 4. Rho-GTPases in Morphogenesis and Differentiation of the Developing Pancreas

    University dissertation from Lund University

    Author : Thomas Greiner; Lunds universitet.; Lund University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin; diabetes; beta cell; cell adhesion; migration; delamination; morphogenesis; tubulogenesis; pancreas; Cdc42; Rho-GTPase; Rac1;

    Abstract : Branched tubular networks constitute the basic structure of many organs to increase surface area and to transport fluids and gases. Glandular organs such as the pancreas arise from multilayered epithelium, which undergoes de novo lumen formation and extensive remodeling and branching. READ MORE

  5. 5. Islet Transplantation a Technical Challenge Studies on Human Pancreas Preservation and Enzymatic Digestion

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : José Caballero-Corbalán; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet transplantation; Human islet isolation; Pancreas preservation; Two-layer method; Perfluorocarbon; Cold storage; Cold ischemia; University of Wisconsin solution; Histidine-tryptophan-ketoglutarate; HTK; Pancreas preservation; Prediction; Collagenase; Trasplante de islotes; Aislamiento de islotes; Preservación del pancreas; Método de las dos capas; Colagenasa; Solución de Wisconsin; HTK; Histidina-triptófano-ketoglutarato; Predicción; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Endocrinology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Endokrinologi; MEDICINE Surgery Surgical research Transplantation surgery; MEDICIN Kirurgi Kirurgisk forskning Transplantationskirurgi; Endokrinologi och Diabetologi; Endocrinology and Diabetology; Cell Research; Cellforskning; Klinisk immunologi; Clinical Immunology;

    Abstract : Islet transplantation has found its niche in diabetes treatment. It has contributed to a better quality of life and better glycemic control of patients with diabetes suffering from severe hypoglycemia that are not eligible for vascularized pancreas transplantation. Islet isolation is a technically challenging procedure. READ MORE