Search for dissertations about: "pancreatic β-cells"

Showing result 1 - 5 of 84 swedish dissertations containing the words pancreatic β-cells.

  1. 1. Enterovirus Infections of β-Cells A Mechanism of Induction of Type 1 Diabetes?

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anna-Karin Berg; Uppsala universitet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; enterovirus; type 1 diabetes; β-cells; human pancreatic islets; picornavirus; chemokines; nitric oxide; Pediatrik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Paediatric medicine; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Pediatrisk medicin;

    Abstract : The process of β-cell destruction that leads to type 1 diabetes (T1D) is incompletely understood and it is believed to be a result of both genetic and environmental factors. Enterovirus (EV) infections of the β-cells have been proposed to be involved, however, the effects of EV infections on human β-cells have been little investigated. READ MORE

  2. 2. Oscillatory Ca2+ signaling in glucose-stimulated murine pancreatic β-cells Modulation by amino acids, glucagon, caffeine and ryanodine

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Meftun Ahmed; Uppsala universitet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; pancreatic β-cells; islets of Langerhans; glucose; Ca2 oscillations; Ca2 transients; potassium; ryanodine; caffeine; glucagon; cAMP; inositol 1; 4; 5-trisphosphate; fura-2; glycine; alanine; arginine; Ca2 channels; rats; lean mice; ob ob mice; leptin; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Oscillations in cytoplasmic Ca2+ concentration ([Ca2+]i) is the key signal in glucose-stimulated β-cells governing pulsatile insulin release. The glucose response of mouse β-cells is often manifested as slow oscillations and rapid transients of [Ca2+] i. READ MORE

  3. 3. ATP Dynamics in Pancreatic α- and β-cells

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Jia Li; Uppsala universitet.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ATP; Ca2 ; β-cell; α-cell; SERCA; SOCE; muscarinic receptor; insulin secretion; glucagon secretion; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Glucose metabolism in pancreatic α- and β-cells is believed to regulate secretion of glucagon and insulin, respectively. In β-cells, ATP links glucose metabolism to electrical activity and insulin secretion. READ MORE

  4. 4. Regulation of organelle Ca²+ in individual pancreatic β-cells

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anders Tengholm; Uppsala universitet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; pancreatic b-cell; inracellular Ca2 stores; furaptra; endoplasmic reticulum; digitonin; a toxin; glucose; ATP; thapsigargin; inositol 1; 4; 5-trisphosphate; ryanodine receptors; cyclic ADP ribose; nicotinic acid adenine dinucleotide phosphate; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : The Ca2+ion plays a fundamental role in the control of a variety of cellular functions, including insulinsecretion from pancreatic β-cells. Whereas the concentration of free Ca2+ in the cytoplasm ([Ca2+]i) ismaintained at low levels (5O-100 nM), some organelles contain high concentrations of the ion. READ MORE

  5. 5. Studies of the Effect of Enterovirus Infection on Pancreatic Islet Cells

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Asma Basheir Elshebani; Uppsala universitet.; [2006]
    Keywords : Medical sciences; type 1 diabetes; Human pancreatic islets; β-cells; chemokines; enterovirus; MEDICIN OCH VÅRD;

    Abstract : Enterovirus (EV) infections have been associated with the pathogenesis of Type 1 Diabetes (T1D). However, the pathway(s) by which EV may induce or accelerate diabetes is not well understood. READ MORE