Search for dissertations about: "pancreatic islets"
Showing result 1 - 5 of 234 swedish dissertations containing the words pancreatic islets.
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1. Leukocytes in Angiogenesis : Learning from Transplanted Pancreatic Islets
Abstract : Angiogenesis, the growth of new blood vessels, is a complex process involving several cell types and molecular signals. Excessive vascular growth is a problem in tumors, and insufficient vascularization hampers the function of transplanted insulin-producing pancreatic islets. READ MORE
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2. CFTR in pancreatic islets
Abstract : AbstractCystic fibrosis (CF) is caused by mutations in the anion channel and protein regulator CFTR. The most common co-morbidity in CF is CF-related diabetes (CFRD) affecting ~50% of adult patients. The etiopathology of CFRD is largely unknown but the destruction of the exocrine pancreas is thought to contribute. READ MORE
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3. Microencapsulation of Pancreatic Islets : A Non-Vascularised Transplantation Model
Abstract : Transplantation of pancreatic islets is a potential treatment of type 1 diabetes that aims to restore normal blood glucose control. By encapsulating the islets in alginate, they can be protected from rejection. READ MORE
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4. Implantation-Site Dependent Differences in Engraftment and Function of Transplanted Pancreatic Islets
Abstract : Transplanting pancreatic islets into the liver through the portal vein is currently the most common procedure in clinical islet transplantations for treating patients with brittle type 1 diabetes. However, most islet grafts fail within a 5-year period necessitating retransplantation. READ MORE
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5. The Microvasculature of Endogenous and Transplanted Pancreatic Islets : Blood Perfusion, Oxygenation and Islet Endocrine Function
Abstract : Type 1 diabetes mellitus affects millions of people worldwide. Islet transplantation is a minimal invasive surgical procedure that restores euglycemia and halts the progression of diabetic complications. However, despite transplantation of islets from multiple donors most patients reverse to hyperglycemia within five years. READ MORE