Search for dissertations about: "pancreatic pathology"

Showing result 1 - 5 of 15 swedish dissertations containing the words pancreatic pathology.

2. 1. Tissue Microarrays for Analysis of Expression Patterns

   Author : Cecilia Lindskog Bergström; Fredrik Pontén; Anna Asplund; Ari Ristimäki; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tissue microarrays; Antibody-based proteomics; Immunohistochemistry; Biomarker discovery; Diabetes; Lung cancer; Influenza virus; Evolution; Pathology; Patologi;

   Abstract : Proteins are essential building blocks in every living cell, and since the complete human genome was sequenced in 2004, researchers have attempted to map the human proteome, which is the functional representation of the genome. One such initiative is the Human Protein Atlas programme (HPA), which generates monospecific antibodies towards all human proteins and uses these for high-throughput tissue profiling on tissue microarrays (TMAs). READ MORE

4. 2. Characterization of the Pancreas in Type 1 and Type 2 Diabetes

   Author : Marcus Lundberg; Oskar Skog; Olle Korsgren; Martha Campbell-Thompson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Type 2 diabetes; HbA1c; interferon-stimulated genes; parasympathetic; axon; cellular stress; islets; exocrine; immunology; leucocytes; inflammation; human; pancreas; Endocrinology and Diabetology; Endokrinologi och Diabetologi; Immunologi; Immunology; Patologi; Pathology;

   Abstract : Diabetes is recognized by hyperglycaemia and polyuria. Complications, reduced quality of life and staggering health-care costs are all derived from the disease. Two subclasses of diabetes are Type 1 diabetes (T1D) and Type 2 diabetes (T2D). READ MORE

5. 3. Functional analysis of Ipf1/Pdx1, MFng and Id during pancreatic growth and differentiation

   Author : Per Svensson; Helena Edlund; Henrik Semb; Umeå universitet; []
   Keywords : pancreas; proliferation; differentiation; signalling; expression; FgfR2IIIb; ErbB3; spondin1; MFng; Id; molekylär medicin genetik och patologi ; molecular medicine  genetics and pathology ;

   Abstract : The pancreas is an endodermally derived organ consisting of three major cell lineages. The endocrine cells, organised into the Islets of Langerhans, regulate blood glucose homeostasis by producing and secreting hormones such as glucagon and insulin into the bloodstream. READ MORE

6. 4. Insulin-Producing Cells, Iron, Oxidative Stress, and Lysosomal Pathology

   Author : Beata Teresa Olejnicka; Enrique Cadenas; Linköpings universitet; []
   Keywords : Insulin-producing cells; redox-active iron; oxidative stress; lysosomes; desfenioxamine; MEDICINE; MEDICIN;

   Abstract : Accumulating evidence suggests that injnries caused by oxygen-derived radicals contribute to the destruction of pancreatic islet ß-cells in autoinnnune diabetes mellitus (diabetes type I, or IDDM). Oxidative stress may be caused by an enhanced production of oxygen-derived radicals, or by a decreased scavenging of such molecules. READ MORE

7. 5. A high-throughput pathology approach for further insight into the role of RBM3 as a biomarker of prognosis and chemotherapy response in human cancer

   Author : Liv Ben Dror; Tumörmikromiljö; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Cancer incidence is increasing and it is the number one cause of death worldwide. Cancer is a highly heterogeneous disease and there is a great need for new early diagnostic, prognostic and treatment predictive biomarkers in order to improve patient outcomes. READ MORE