Search for dissertations about: "paola terrazas"

Found 1 swedish dissertation containing the words paola terrazas.

2. 1. SARs for the Antiparasitic Plant metabolite Pulchrol

   Author : Paola Terrazas Villarroel; Centrum för analys och syntes; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; pulchrol; pulchral; SARs; antiparasitic; Leishmania braziliensis; Leishmania amazonensis; Trypanozoma cruzi; Bourreria pulchra; Leishmaniasis; Chagas disease; Synthesis; Pharmacophore; ADMET;

   Abstract : Pulchrol, a natural compound isolated from the roots of the vegetal specie Bourreria pulchra has been shown to possess potential antiparasitic activity toward Trypanosomatids, particularly against Trypanosoma cruzi, which causes the Chagas disease; and moderately against Leishmania species, responsible for Leishmaniasis. In this investigation, several pulchrol analogues were prepared and assayed toward T. READ MORE