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Showing result 1 - 5 of 11 swedish dissertations matching the above criteria.

  2. 1. Immunological aspects of papillary thyroid carcinoma

    Author : Steven D. Lucas; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Papillary thyroid carcinoma; immunology; tumor antigens; RET proto-oncogene; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Abstract : Papillary thyroid carcinoma (PTC) is a puzzling disease. Although approximately 70% of patients with PTC have regional lymph node metastases at initial surgery, the long term survival is over 95%. READ MORE

  4. 2. Molecular aspects of post-Chornobyl and sporadic papillary thyroid carcinoma

    Author : Andrii Dinets; Karolinska Institutet; Karolinska Institutet; []
    Keywords : papillary thyroid carcinoma;

    Abstract : Papillary thyroid carcinoma (PTC) exhibits various molecular abnormalities, both when sporadic and radiation-related. PTC is still diagnosed in adult individuals who were younger than 18 years at the time of the Chornobyl accident in 1986 and lived within the contaminated area. READ MORE

  5. 3. Clinical and molecuar studies of papillary thyroid carcinoma : with an emphasis on prognostic factors

    Author : Petra Kjellman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Papillary thyroid carcinoma; MIB-1; RET-proto-oncogene; RET PTC; CGH; prognosis;

    Abstract : Thyroid cancer accounts for approximately 1% of all cancers reported. In Sweden 45/100, 000 inhabitants annually present with thyroid carcinoma. There are four different variants of thyroid carcinoma: papillary thyroid carcinoma (PTC), follicular thyroid carcinoma, medullary thyroid carcinoma and anaplastic thyroid carcinoma. READ MORE

  6. 4. Genetic Characterization and Identification of Novel Treatment Targets in Anaplastic Thyroid Carcinoma

    Author : Naveen Ravi; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaplastic thyroid cancer; copy number alterations; somatic mutations; mutational signatures; DNA methylation analysis; Gene expression analysis;

    Abstract : Anaplastic thyroid cancer (ATC) is a rare and highly aggressive thyroid malignancy, usually resistant to conventional therapeutic strategies. The prognosis of ATC is extremely poor with a median survival rate of 6 months. Current treatment therapy includes surgical resection in combination with external radiotherapy and chemotherapy. READ MORE

  7. 5. Molecular genetic studies of human thyroid tumors

    Author : Tony Frisk; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Follicular thyroid tumors; tumor progression; Cowden disease; PTEN; CGH; RET; medullary thyroid carcinoma; MEN 2; anaplastic carcinoma.;

    Abstract : Tumors of the thyroid gland are common among the general population, but only a small proportion is malignant. The vast majority of thyroid tumors are benign, so called follicular adenomas. Sometimes subtypes such as atypical adenomas and adenomas with oxyphil, i.e. READ MORE