Search for dissertations about: "paralog"

Showing result 1 - 5 of 11 swedish dissertations containing the word paralog.

  2. 1. Porins of Borrelia burgdorferi

    Author : Marija Pinne; Sven Bergström; Magnus Höök; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lyme disease; P13; paralog; P66; channel-forming activity; porin; Medical microbiology; Medicinsk mikrobiologi;

    Abstract : Borrelia burgdorferi is a pathogenic spirochete which cycles between its arthropod vector and vertebrate host. If transmitted to humans, B. burgdorferi causes Lyme disease, an infection which can impair different organs, such as the skin, joints, nervous system and heart. READ MORE

  4. 2. Chromatin remodeling and dna topology in transcription and genome stability

    Author : Jenna Persson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Eukaryotic DNA is wrapped around histone proteins to form nucleosomes, the fundamental repeating unit of chromatin. DNA packaging into chromatin both solves and creates problems. It allows the centimeters, or even meters, of DNA that constitute a eukaryotic genome to fit inside a micrometer-scale cell nucleus. READ MORE

  5. 3. The elephant in the cell : A multifaceted undertaking to uncover the molecular principles behind lymphatic endothelial cell identity

    Author : Virginia Panara; Katarzyna Koltowska; Taija Mäkinen; Marcel den Hoed; Sarah de Val; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Lymphatic endothelium; Development; Epigenetic; Biologi med inriktning mot zoologisk utvecklingsbiologi; Biology with specialization in Animal Development;

    Abstract : The lymphatic vascular network is composed of a series of blind ended vessels, and is involved in physiological functions such as fluid homeostasis, lipid metabolism and immune trafficking. Despite lymphatic endothelial cells being derived from multiple organs, they share common molecular denominators, including the expression of the transcription factor Prox1. READ MORE

  6. 4. Exploring the Cell Cycle of Archaea

    Author : Magnus Lundgren; Rolf Bernander; William Margolin; Uppsala universitet; []
    Keywords : Microbiology; Archaea; Cell cycle; Replication; Mitosis; Cell division; Mikrobiologi;

    Abstract : Archaea is the third domain of life, discovered only thirty years ago. In a microscope archaea appear indistinguishable from bacteria, but they have been shown to be more closely related to eukaryotes than to bacteria. Especially central information processing is homologous to that of eukaryotes. READ MORE

  7. 5. Prediction of function shift in protein families

    Author : Saraswathi Abhiman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Protein function; Divergence; Function shift; Subfamily;

    Abstract : With the availability of a large number of complete genome sequences, it has become essential to annotate the protein sequences derived from them as precisely as possible. Even though presently available computational methods can predict broad functionality for most protein sequences, there is room for improvement in order to get more precise functional annotation. READ MORE