Search for dissertations about: "parameterization"

Showing result 21 - 25 of 133 swedish dissertations containing the word parameterization.

  2. 21. Computational Studies of HIV-1 Protease Inhibitors

    Author : Wesley Schaal; Garland Marshall; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; HIV Protease; 3D-QSAR; CoMFA; Molecular Modelling; Force Field Parameterization; Quantum Mechanics; DFT; Enzyme Kinetics; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Organic Pharmaceutical Chemistry; Organisk farmaceutisk kemi;

    Abstract : Human Immunodeficiency Virus (HIV) is the causative agent of the pandemic disease Acquired Immune Deficiency Syndrome (AIDS). HIV acts to disrupt the immune system which makes the body susceptible to opportunistic infections. Untreated, AIDS is generally fatal. READ MORE

  4. 22. Solute Transport Across Scales : Time Series Analyses of Water Quality Responses to Quantify Retention and Attenuation Mechanisms in Watersheds

    Author : Joakim Riml; Anders Wörman; Aaron I. Packman; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Solute transport modeling; Transient storage; Tracer test; Central temporal moments; Spectral analysis; Parameterization;

    Abstract : The intra-continental movement of waterborne contaminants is governed by the distribution of solute load in the landscape along with the characteristics and distribution of the hydrological pathways that transport the solutes. An understanding of the processes affecting the transport and fate of the contaminants is crucial for assessments of solute concentrations and their environmental effect on downstream recipients. READ MORE

  5. 23. Modelling biomolecular interactions

    Author : Johan Bredenberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Computational chemistry; molecular dynamics; nuclear receptors; force field parameterization; zinc fingers; DNA; proteins.;

    Abstract : Computational approaches for understanding and aiding in molecular biology has increased in significance over the last decades, where a wealth of biochemical experiments have provided a solid ground for developing computer models that can be used to predict unresolved issues within biology. Molecular dynamics (MD) is one of these methods, based on classical laws, and suitable for handling large macromolecules in their natural environment, water. READ MORE

  6. 24. Studies of stratocumulus-topped boundary layers using a numerical weather prediction model

    Author : Robert Sigg; Peter Duynkereke; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; meteorologi; Meteorology;

    Abstract : Persistent stratocumulus clouds are commonly observed in many areas on Earth. In general, stratocumulus clouds cool the Earth-atmosphere system due to their influence on the radiation budget. It is therefore essential to describe such clouds accurately in climate and numerical weather prediction models. READ MORE

  7. 25. Arterial mechanics : noninvasive identification of constitutive parameters and residual stress

    Author : Jonas Stålhand; Gerhard A. Holzapfel; Linköpings universitet; []
    Keywords : TECHNOLOGY; TEKNIKVETENSKAP;

    Abstract : This thesis concerns the mechanical modelling of arteries, and particularly a method to identify parameters describing the mechanical properties using only clinically obtainable in vivo measurements. The artery is modelled as a fibre reinforced, incompressible, thick-walled cylinder subjected to large deformations and a residual stress field. READ MORE