Search for dissertations about: "parasite ligands"

Showing result 1 - 5 of 10 swedish dissertations containing the words parasite ligands.

  2. 1. Studies on malaria blood stage infection and host responses

    Author : Lili Xu; Klavs Berzins; Adrian Luty; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Malaria; cytokines; parasite ligands; merozoite released soluble proteins MRSPs ; molekylär biovetenskap; Molecular Biosciences;

    Abstract : The challenges in controlling malaria infectious disease are increasing due to drug resistance and incomplete immunity induced by malaria infection. Moreover there is no effective vaccine available against malaria blood stage infection. READ MORE

  4. 2. Identification of new proteins and biological processes in the apicomplexan Toxoplasma gondii

    Author : Silvia Botero-Kleiven; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The apicomplexan protozoan Toxoplasma gondii is a ubiquitous parasite of humans and animals. Entering its host through the digestive system, it possesses the ability to rapidly disseminate in the body and infect a wide range of tissues and cells. READ MORE

  5. 3. Polyamine Pathway as Drug Target against Malaria

    Author : Janina Sprenger; Biogena aminer; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amino acid insertions; Crystallography; polyamine pathway; drug design; enzyme inhibition; ITC; ligand binding; malaria; Plasmodium falciparum; S-Adenosylmethionine decarboxylase; spermidine synthase.;

    Abstract : Malaria, caused by the protozoan parasite Plasmodium falciparum is responsible for about 600.000 death cases every year. Mainly affected are populations of subtropical countries in Africa and the largest groups of victims are children below the age of 5 years. READ MORE

  6. 4. Organometallic complexes with antimalarial properties

    Author : Lotta Glans; Kemisk fysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioorganometallic chemistry; Chloroquine; Antimalarial; Drug resistance; Organometallic; Arene;

    Abstract : Malaria is a serious disease that causes around 800 000 deaths per year. Current malaria control efforts are hampered by the widespread resistance to common antimalarial drugs, such as the 4-aminoquinoline derivative called chloroquine. READ MORE

  7. 5. Variant antigens at the infected red cell surface in Plasmodium falciparum malaria

    Author : Victor Fernandez; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Plasmodium falciparum; blood stages; variant antigens; var PfEMP1; rif RIFIN; adhesive phenotypes; cytoadherence; endothelial receptor; PECAM-1 CD31; rosetting; heparan sulphate;

    Abstract : Disease severity in Plasmodium falciparum infections is, to a large extent, a consequence of the parasite's efficient escape from die human host defences. Sequestration and antigenic variation are two evasion mechanisms featured by P.falciparum. READ MORE