Search for dissertations about: "parkinsons scanning"

Found 5 swedish dissertations containing the words parkinsons scanning.

  1. 1. Functional brain imaging of cognitive status in Parkinson's disease

    Author : Urban Ekman; Johan Eriksson; Lars Nyberg; Lars Forsgren; Oury Monchi; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; functional MRI; Mild cognitive impairment; Working memory; Parkinson’s disease dementia; BOLD;

    Abstract : Parkinson’s disease (PD) is next to Alzheimer’s disease (AD) the second most common neurodegenerative disease. PD has traditionally been characterised as a motor disorder, but more recent research has revealed that cognitive impairments are frequent. READ MORE

  2. 2. Stereotactic imaging in functional neurosurgery

    Author : Hidehiro Hirabayashi; Patric Blomstedt; Takaomi Taira; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Deep brain stimulation; pallidotomy; thalamotomy; Parkinson s disease; essential tremor; CT; MRI; neurokirurgi; Neurosurgery;

    Abstract : Background: The birth of stereotactic functional neurosurgery in 1947 was to a great extent dependent on the development of ventriculography. The last decades have witnessed a renaissance of functional stereotactic neurosurgery in the treatment of patients with movement disorders. READ MORE

  3. 3. Neuropeptidomics – Methods and Applications

    Author : Karl Sköld; Per E Andrén; Per Svenningsson; Chris Shaw; Uppsala universitet; []
    Keywords : Pharmaceutical pharmacology; mass spectrometry; proteomics; peptidomics; neuropeptide; bioinformatics; Farmaceutisk farmakologi;

    Abstract : The sequencing of genomes has caused a growing demand for functional analysis of gene products. This research field named proteomics is derived from the term proteome, which by analogy to genome is defined as all proteins expressed by a cell or a tissue. READ MORE

  4. 4. Oligomerization of human and bacterial frataxin : Structural and functional studies

    Author : Mostafa Abdalkhalik; Biokemi och Strukturbiologi; []
    Keywords : Frataxin; Friedreich’s ataxia; iron; reactive oxiden species; protein oligomerization; SAXS; EM; cross-linking; XAFS; nano- DSF;

    Abstract : Friedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disease caused by defeciency in frataxin, a highly conserved protein central to iron homeostasis in mirochondria. The function of frataxin is related to its capability to bind, store and deliver iron to different biochemical process such as iron-sulfur cluster assembly and heme biosynthesis. READ MORE

  5. 5. Cellular Effects of Cystatins

    Author : Samar Hunaiti; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cystatin C; Cystatin D; Galectin-1; Puncta assay; HoloMonitor; Cancer cells; Apoptosis; Cathepsin C;

    Abstract : The exact cellular functions of cystatins are still unknown, and the molecular mechanism leading to their internalization into cells is not yet fully understood. Commonly the cystatins are known to inhibit human lysosomal cysteine proteases (cysteine cathepsins) and it is supposed that this is their primary physiological role. READ MORE