Search for dissertations about: "partial unfolding"

Showing result 1 - 5 of 10 swedish dissertations containing the words partial unfolding.

  2. 1. The Folding Energy Landscape of MerP

    Author : Ann-Christin Brorsson; Bengt-Harald Jonsson; Daniel Otzen; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; protein folding and stability; hydrogen exchange; intermediate; partial unfolding; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

    Abstract : This thesis is based on studies, described in four papers, in which the folding energy landscape of MerP was investigated by various techniques. MerP is a water-soluble 72 amino acid protein with a secondary structure consisting of four anti-parallel β-strands and two α-helices on one side of the sheet in the order β1α1β2β3α2β4. READ MORE

  4. 2. Sequential convergence for functions and operators

    Author : Jeanette Silfver; Mårten Gulliksson; Anders Holmbom; Nils Svanstedt; Mittuniversitetet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; homogenization; two-scale convergence; G-convergence; H-convergence; partial differential equations; functional analysis; heterogeneous media; MATHEMATICS; MATEMATIK;

    Abstract : The mathematical discipline homogenization theory is closely related to convergence issues. In this thesis different types of convergence are studied and put in relation to each other. We consider the classical concepts of G- and H-convergence and compensated compactness. READ MORE

  5. 3. Biophysical Studies of Protein Folding, Aggregation and Interactions with Molecular Chaperones

    Author : Per Hammarström; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The information for a protein to fold correctly into a well defined three-dimensional functional structure is embedded in the primary sequence. Much effort has been devoted to characterize the nature of the unfolded state, since this state represents the starting point of the folding reaction. READ MORE

  6. 4. Compact Constraints for Verification of Well Quasi-Ordered Programs

    Author : Aletta Nylén; Parosh Abdulla; Kaisa Sere; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Computer science; Datavetenskap;

    Abstract : In this thesis we present algorithms and constraint systems for efficient verification of infinite-state transition systems that are monotonic with respect to a well quasi-ordering. A major problem in verification of infinite-state systems is constraint explosion, that is, the number of constraints generated during analysis is too large. READ MORE

  7. 5. Nuclear mechanisms in cell death induced by HAMLET (human alpha-lactalbumin made lethal to tumour cells)

    Author : Caroline Düringer; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; virology; mykologi; bakteriologi; virologi; mycology; bacteriology; Microbiology; chromatin; histones; apoptosis; alpha-lactalbumin; programmed cell death;

    Abstract : HAMLET (human alpha-lactalbumin made lethal to tumour cells), a protein-lipid complex originally isolated from human milk, induces programmed cell death selectively in tumour cells. It consists of partially unfolded alpha-lactalbumin in complex with oleic acid. READ MORE