Search for dissertations about: "particle stability"

Showing result 1 - 5 of 232 swedish dissertations containing the words particle stability.

  2. 1. Surface reactivity, stability, and mobility of metal nanoparticles in aqueous solutions : Influence of natural organic matter and implications on particle dispersion preparation

    Author : Sulena Pradhan; Inger Odnevall Wallinder; Jonas Hedberg; Eva Blomberg; Emma Strömberg; Kerstin Forsberg; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nanoparticles; freshwater; di-hydroxybenzoic acid; humic acid; copper; aluminium; manganese; dissolution; agglomeration; stability; complexation; Kemi; Chemistry;

    Abstract : The growing development of nanotechnology has resulted in an increased use of nanoparticles (NPs) in various applications ranging from medicine, military, to daily consumer products. There is a concern that NPs can be dispersed into the environment in various ways, for example to air and water during manufacture, use, incineration or recycling of products and thus pose a risk to health and the environment. READ MORE

  4. 2. Understanding Adhesive Mixtures for Inhalation : Particle Dynamics Modelling and Segregation Experiments

    Author : Sohan Sarangi; Göran Frenning; Göran Alderborn; Kyrre Thalberg; Johannes Khinast; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inhalation; adhesive mixtures; dry powder inhaler; discrete element method; segregation; stability; modeling; Galenisk farmaci; Pharmaceutics; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Pulmonary route has been used as a source of drug delivery to lungs for centuries. Drugformulation decides the type of inhaler devices such as pressurized metered-dose inhalers(pMDIs), nebulizers and dry powder inhalers (DPIs). READ MORE

  5. 3. Transition in Particle-laden Flows

    Author : Joy Klinkenberg; Luca Brandt; Shuisheng He; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Transition; modal analysis; non-modal analysis; multi-phase flow; particle-laden; heavy particles; light particles;

    Abstract : This thesis presents the study of laminar to turbulent transition of particle laden flows. When a flow becomes turbulent, the drag increases one order of magnitude compared to a laminar flow, therefore, much research is devoted to understand and influence the transition. READ MORE

  6. 4. Preparation of Pharmaceutical Powders using Supercritical Fluid Technology : Pharmaceutical Applications and Physicochemical Characterisation of Powders

    Author : Sitaram Velaga; Johan Carlfors; Kristiina Järvinen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Supercritical fluid; Gas Anti-Solvent; SEDS; Crystallisation; Particle design; Polymorphs; Dry powder inhalation; Solid-state behaviour; Therapeutic proteins; Precipitation; Stability; Recombinant human growth hormone hGH ; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Abstract : The main aim of the thesis was to explore the potential of supercritical fluid (SF) techniques in the field of drug delivery. In particular, the relatively recently developed solution-enhanced dispersion by supercritical fluids (SEDS) technology has been employed in the preparation of particles/powders. READ MORE

  7. 5. Molecular Mechanisms Influencing the Performance of Amorphous Formulations for Poorly Water-Soluble Drugs

    Author : Khadijah Edueng; Christel Bergström; Denny Mahlin; Michael Hageman; Uppsala universitet; []
    Keywords : Amorphous formulation; crystallisation; supersaturation; glass-forming ability; physical stability; glass stability; spray-dried solid dispersion; dissolution; promiscuous glass former; poorly-soluble drug; solid-to-solid; solution-mediated; particle-associated; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Crystallisation is a concern for amorphous formulation because it compromises the solubility-enhancing benefit gained from amorphisation. Traditionally, amorphous formulation had been designed primarily based on trial-and-error approach. READ MORE