Search for dissertations about: "parvalbumin"

Showing result 1 - 5 of 31 swedish dissertations containing the word parvalbumin.

  2. 1. Phenotypic Specification of Striatal Progenitors; Evidence for both cell-autonomous and environmental control as studied by transplantation into the adult and developing rodent brain

    Author : Martin Olsson; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; striatal projection neurons; striatal development; somatostatin; parvalbumin; neuronal differentiation; neural transplantation; medial ganglionic eminence; lateral ganglionic eminence; forebrain dvelopment; cholinergic; embryonic; thyroid transcription fa; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Abstract : The striatum is the major component of the ventral telencephalon and basal ganglia, involved in the processing of cortical information. The vast majority of the neuronal population in the striatum are striatal projection neurons, with connection to the globus pallidus and substantia nigra. READ MORE

  4. 2. Generating GABAergic interneurons through reprogramming and differentiation strategies : English

    Author : Andreas Bruzelius; Regenerativ neurofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; interneurons; neuronal reprogramming; glial progenitor cells; neuronal differentiation; human embryonic stem cells; induced neurons; somatostatin; parvalbumin;

    Abstract : In recent years reprogramming techniques, differentiation protocols, and sequencing analysis have opened a field for generating and studying human-derived neurons with greater potential than ever before. This has generated a large number of studies with the goal of deriving bona fide neurons. READ MORE

  5. 3. Stroke recovery activity-dependent mechanisms

    Author : Miriana Quattromani; Neurokirurgi; []
    Keywords : Stroke recovery; Photothrombosis; Enriched environment; Bioluminescence imaging; Toll-like receptor 2; Microglia; Neurons; Extracellular matrix; Perineuronal nets; Aggrecan; Proteases; Parvalbumin; Resting-state functional connectivity;

    Abstract : Stroke is the leading cause of disability in developed countries and among the major causes of death worldwide. During a stroke, neurons deprived of their normal metabolic substrates cease to function in seconds and show signs of structural damage after only a few minutes which result in the impairment of sensory and motor function. READ MORE

  6. 4. Roles of intermolecular interactions in amyloid fibril formation mechanisms

    Author : Tony Werner; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; disulfide-bonds; Atox1; α-synuclein; Aggregation; protein interactions; Parkinson’s disease; β-parvalbumin; macromolecular crowding; osmolytes; Amyloid fibrils;

    Abstract : Amyloid fibrils, a major pathological feature of several neurodegenerative disorders, are highly stable, insoluble aggregates of misfolded proteins. The formation of such aggregates involves a complex equilibrium between protein monomers, different on- and off-pathway transient oligomeric species, and amyloid fibrils. READ MORE

  7. 5. On the role of parvalbumin interneurons in neuronal network activity in the prefrontal cortex

    Author : Nicolas Gustavo Guyon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The prefrontal cortex (PFC) is an area important for executive functions, the initiation and temporal organization of goal-directed behavior, as well as social behaviors. Inhibitory interneurons expressing parvalbumin (PV) have a vital role in modulating PFC circuit plasticity and output, as inhibition by PV interneurons on excitatory pyramidal neurons regulates the excitability of the network. READ MORE