Search for dissertations about: "patch clamp"

Showing result 21 - 25 of 88 swedish dissertations containing the words patch clamp.

2. 21. K+ channels in the inner ear : electrophysiological and molecular studies

   Author : Guihua Liang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Cochlea; gene expression; hair cell; immunohistochemistry; KCNQ; lead; M current; mercury; patch clamp; RT-PCR; voltage-gated potassium channels;

   Abstract : Potassium channels are involved in several fundamental cellular processes. Heavy metals, such as mercury and lead, are widespread toxic pollutants and have been shown to act on various ion channels in the central nervous system. READ MORE

4. 22. Histochemical, biochemical and electrophysiological studies on dorsal root ganglion cultures : focusing on galanin, neuropeptide Y and glutamate

   Author : Nora Kerekes; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Acute and long-term DRG cultures; aFGF; BDNF; bFGF; bradykinin; excitability; galanin; glutamate; leukemia inhibitory factor; neuropeptide Y; : NGF; regeneration; whole cell patch clamp.;

   Abstract : Galanin (Gal) and neuropeptide Y (NPY) are two peptides, which are strongly up- regulated in a population of dorsal root ganglion (DRG) neurons after peripheral nerve injury (axotomy). Both peptides may be involved in the control of pain sensation, especially after nerve injury (neuropathic pain). READ MORE

5. 23. Adult human neural stem cells : properties in vitro and as xenografts in the spinal cord

   Author : Ulf Westerlund; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Action potential; adult; allodynia; auto-transplantation; endoscope; glutamate; hippocampus; human; neural stem cells; p75; patch clamp; progenitor; spinal cord injury; subventricular zone; synapse; transplantation;

   Abstract : Though the presence of stem cells in the adult human brain has been presented earlier, much has yet to be discovered about these cells. However, the mere potential of these cells has had a significant impact of how we today evaluate the regenerative capacity of the central nervous system and, importantly, on the possible means for science to provide insights in neural repair. READ MORE

6. 24. Growth of parathyroid glands : genetic and functional aspects

   Author : Stiina Välimäki; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Parathyroid; primary hyperparathyroidism; secondary hyperparathyroidism; parathyroid carcinoma; chromosome 1; HDAC1; HRPT2; CASR; CAS; VDR; PTH; loss of heterozygosity; tumor suppressor gene; patch clamp; membrane potential; K channels;

   Abstract : Ca2+ is an essential ion with a variety of important functions in the body and it is crucial that the Ca2+ levels are precisely regulated. One of the hormones regulating these processes is parathyroid hormone (PTH) secreted from the parathyroid glands. READ MORE

7. 25. Calcium signaling in astroglial cells. Noradrenergic effects and regulation

   Author : Håkan Muyderman; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Astrocytes; Neurons; Noradrenaline; Glutamate; Fluorometry; Fura-2; Fluo-3; PBFI; Digital imaging; Voltage-patch-clamp; Whole-cell currents; Calcium; Potassium; Intercellular communication; Glutamate release; Neuron-glial interactions.;

   Abstract : Astroglial cells are the most common cell type in the central nervous system and express a wide array of ion channels and neurotransmitter receptors. The cells organize into multicellular networks and exhibit a calcium-based excitability in which receptor-mediated calcium elevations propagate as intercellular waves over considerable distances. READ MORE