Search for dissertations about: "pathogenesis of parasite"

Showing result 16 - 20 of 22 swedish dissertations containing the words pathogenesis of parasite.

  2. 16. Dysregulation of receptor induced apoptosis during human leishmaniasis : a possible mechanism of skin ulceration

    Author : Liv Eidsmo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cutaneous leishmaniasis; visceral leishmaniasis; Death Receptors; Fas; FasL; Apoptosis;

    Abstract : Leishmaniasis is endemic in 88 countries and 12 million people per year have been estimated to be at risk of infection. The causative agent, the protozoan Leishmania, is spread by sand-flies and infects macrophages in the mammalian host. Leishmaniasis in humans form a spectrum of clinical presentations. In cutaneous leishmaniasis (CL) caused by L. READ MORE

  4. 17. Impact of malaria on B-cell homeostasis and Epstein-Barr virus reactivation : endemic Burkitt's lymphoma pathogenesis

    Author : Arnaud Chêne; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Over recent years, the concept that many diseases can be aetiologically linked to infection by more than one pathogen has gained increased attention and awareness. Plasmodium falciparum (P. READ MORE

  5. 18. Virulence in Plasmodium falciparum malaria : mechanisms of PfEMP1-mediated rosetting

    Author : Davide Angeletti; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Malaria is one of the most important infectious diseases in the world and the Plasmodium falciparum parasite is the causative agent of most of the severe cases. The pathogenesis of the disease is complex but sequestration and hence microvascular obstruction is associated with virulence of the parasite. READ MORE

  6. 19. Exploration of factors that influence Plasmodium falciparum fitness and virulence

    Author : Madle Sirel; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Malaria is an ancient disease that still has profound impact on human population. The virulence of the most lethal malaria parasite, Plasmodium falciparum, can be attributed to several features of the parasite. P. falciparum is known for its indiscriminate red blood cell (RBC) invasion and aptitude for cytoadherence. READ MORE

  7. 20. Dissecting the complexity of human susceptibility to Plasmodium falciparum malaria: genetic approaches

    Author : Valentina D Mangano; Marita Troye-Blomberg; Marta Alarcon; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunology; genetics; malaria; Immunology; Immunologi; immunologi; Immunology;

    Abstract : There are many aspects of the immunology of P. falciparum infection that are not understood. Genetic approaches are of great value for dissecting the complexity of immune responses to malaria in natura by providing new insights into molecular interactions between the parasite and the host. READ MORE