Search for dissertations about: "pathology"

Showing result 11 - 15 of 920 swedish dissertations containing the word pathology.

  2. 11. Alzheimer's Disease Neuropathological Change and neuronal and glial alterations in patients with idiopathic Normal Pressure Hydrocephalus

    Author : Sylwia Libard; Irina Alafuzoff; Anna Dimberg; Per Kristian Eide; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; idiopathic Normal Pressure Hydrocephalus; Alzheimer’s disease; amyloid β; hyperphosphorylated τ; Patologi; Pathology;

    Abstract : Alzheimer’s disease Neuropathological Change (ADNC), i.e. amyloid β (Aβ) and hyperphosphorylated τ (HPτ), is seen in excess in the brains of subjects with AD. READ MORE

  4. 12. Altered proteins in the aging brain

    Author : Adila Elobeid; Irina Alafuzoff; Lena Claesson-Welsh; Thomas Brännström; Uppsala universitet; []
    Keywords : Cognitively unimpaired subjects; Hyperphosphorylated tau; Beta amyloid; Alpha-synclein; Transactive response DNA binding protein 43; Patologi; Pathology;

    Abstract : The classification of neurodegenerative disorders is based on the major component of the protein aggregates in the brain. The most common altered proteins associated with neurodegeneration are Hyperphosphorylated tau (HPt), beta amyloid (Aβ), alpha-synclein (αS) and transactive response DNA binding protein 43 (TDP43). READ MORE

  5. 13. Measuring Health : On the Theoretical Foundations of Health Status Evaluations

    Author : Amanda Thorell; Sören Häggqvist; Richard Dawid; Elselijn Kingma; Stockholms universitet; []
    Keywords : HUMANIORA; HUMANITIES; biostatistical theory; disease; disposition; efficiency; function; health; pathology; philosophy of medicine; physiology; reference class; filosofi; Philosophy;

    Abstract : This thesis is about the notions of health and pathology in medical theory. I develop a theory, which defines ‘health’ and ‘pathology’ in a way that solves several problems with earlier suggestions of how to define these terms. I call the theory ‘the disposition profile efficiency theory’, abbreviated ‘the DPE-theory’. READ MORE

  6. 14. PET and the Multitracer Concept: An Approach to Neuroimaging Pathology

    Author : Henry Engler; Bengt Långström; Göran Hedenstierna; Juha Rinne; Uppsala universitet; []
    Keywords : Neurosciences; PET Positron Emission Tomography ; multitracer; neuroimaging pathology; astrocytes; microglia; neurodegeneration; amyloid; AD; CJD; PD; Neurovetenskap;

    Abstract : Patients suffering from different forms of neurodegenerative diseases, such as: Creutzfeldt Jacob Disease (CJD), Alzheimer disease (AD), mild cognitive impairment (MCI), frontotemporal dementia and Parkinson’s disease (PD) were examined with Positron Emission Tomography (PET) and the combination of different radiotracers: 15O-water, N-[11C-methyl]-L-deuterodeprenyl (DED), [18F] 2-fluorodeoxyglucose: (FDG), N-methyl-[11C]2-(4-methylaminophenyl)-6-hydroxybenzothiazole (PIB) and L-[11C]-3,4-dihydroxiphenyl-alanine (DOPA). The radiotracers and the combinations of different radiotracers were selected with the intention to detect, in the brain, patterns of neuronal dysfunction, astrocytosis, axon degeneration or protein aggregation (amyloid), in the brain which are pathognomonic for specific diseases and may contribute to improve clinical differential diagnoses. READ MORE

  7. 15. The matter of white matter in Alzheimer's disease. -On white matter disease from neuropathology and neuroimaging to clinical presentation

    Author : Martin Sjöbeck; Lund Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; medicinsk instrumentering; tomografi; radiologi; Klinisk fysiologi; medical instrumentation; tomography; radiology; executive dysfunction; Clinical physics; magnetic resonance imaging; diffusion tensor imaging; neuropathology; microvascular pathology; astrocytes; myelin; oligodendrocytes; white matter disease; Alzheimer s disease; neuropsychology; neuropsykologi; Neurologi; neurophysiology; neurofysiologi; Psychiatry; clinical psychology; psychosomatics; Psykiatri; klinisk psykologi; psykosomatik; Neurology;

    Abstract : Alzheimer's disease (AD) is the most prevalent type of dementing disorder. The cortical pathology of AD has been recognized for almost a century. In later years, an associated pathological feature of AD has been identified which affects the white matter. READ MORE