Search for dissertations about: "pathways of infections"

Showing result 6 - 10 of 122 swedish dissertations containing the words pathways of infections.

  2. 6. Adenoviral Control of RNAi/miRNA Pathways in Human Cells

    Author : Ning Xu; Göran Akusjärvi; Fredrik Söderbom; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; RNAi; miRNA; VA RNA; Virology; Virologi;

    Abstract : RNA interference (RNAi) is a diverse, conserved regulatory mechanism in eukaryotic cells, which silences the target gene expression in a homology-dependent manner. Although it has been well documented that RNAi is an antiviral mechanism in plants and insects, it is still unclear whether RNAi naturally limits viral infections in vertebrates. READ MORE

  4. 7. Oral Disease and Health Patterns : Dental and Cranial Paleopathology of the Early Iron Age Population at Smörkullen in Alvastra, Sweden

    Author : Carola Liebe-Harkort; Jan Storå; SOFIA TRANÆUS; Simon Hillson; Stockholms universitet; []
    Keywords : HUMANIORA; HUMANITIES; Smörkullen; Alvastra; Sweden; Early Iron Age; dental disease; cranial lesion; caries diagnostics; pathways of infections; dietary patterns; environment; health; Historical osteology; Historisk osteologi; osteoarkeologi; Osteoarchaeology;

    Abstract : In skeletal remains of ancient populations, evidence of dental and craniofacial pathology is often well preserved in the form of lesions on the teeth or bones. Meticulous, detailed recording of these lesions provides baseline data on which a realistic assessment can be made of the probable impact of dental diseases and its sequelae on health of these earlier populations. READ MORE

  5. 8. Growth in Aging Colonies : The Importance of Being Different

    Author : Marie Wrande; Diarmaid Hughes; Måns Ehrenberg; Mikael Rhen; Uppsala universitet; []
    Keywords : ;

    Abstract : The accumulation of rifampicin resistant (RifR) mutants in aging bacterial colonies has previously been attributed to stress-induced mutagenesis. Mutations giving rise to RifR are located in the rpoB gene, coding for the β subunit of RNA polymerase, RpoB. READ MORE

  6. 9. Studies of the pathogenesis of Enterohemorrhagic Escherichia coli infections: pathogen virulence factors and host response

    Author : Carla Calderon Toledo; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; host-pathogen; MyD88; TLRs; LEE; Shiga toxin; HUS; EHEC; EPEC; immune response; virulence factors;

    Abstract : Enterohemorrhagic Escherichia coli (EHEC) is a highly virulent pathogen that can cause diarrhea and a life-threatening disease known as hemolytic uremic syndrome. EHEC possess an array of virulence factors that can exert severe consequences in the host. Shiga toxin constitutes a key virulence factor. READ MORE

  7. 10. Intracellular pathways involved in formation and degradation of prions

    Author : Elin Allard; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Prions cause invariably fatal neurodegenerative diseases, in which a misfolded host-encoded protein appears to be the main, if not the only, component of the infectious agent. During disease, a normal cellular protein, PrPC, is converted to a disease-related isoform, PrPSc, by a post-translational process that might require auxiliary cellular cofactors. READ MORE