Search for dissertations about: "patologi Cellbiologi Medicinsk cellbiologi"
Showing result 1 - 5 of 7 swedish dissertations containing the words patologi Cellbiologi Medicinsk cellbiologi.
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1. Extracellular Matrix Based Materials for Tissue Engineering
Abstract : The extracellular matrix is (ECM) is a network of large, structural proteins and polysaccharides, important for cellular behavior, tissue development and maintenance. Present thesis describes work exploring ECM as scaffolds for tissue engineering by manipulating cells cultured in vitro or by influencing ECM expression in vivo. READ MORE
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2. Extracellular Matrix and Connective Tissue Cells of the Tumor Microenvironment
Abstract : In addition to malignant cells, solid tumors comprise supporting stromal tissue that consists of extra cellular matrix (ECM), connective tissue cells, inflammatory cells and blood vessels. The stromal compartment and the malignant cells together shape the tumor microenvironment that in turn determines tumor progression and efficacy of anti-tumor treatments. READ MORE
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3. Investigation of immune cell-derived factors as potential biomarkers in patients with colorectal cancer
Abstract : Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer related death. It is a heterogeneous disease involving multiple molecular pathways that result in differing phenotypes. Individual variability in CRC susceptibility is influenced by genetic variation, such as single nucleotide polymorphisms (SNPs). READ MORE
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4. Neuromuscular injuries and pharyngeal dysfunction in snorers and sleep apnea patients : a study on pathological changes in the human soft palate and its relationship with swallowing dysfunction
Abstract : Obstructive sleep apnea (OSA) is a prevalent progressive sleep disorder with serious negative health consequences. Although several risk factors such as obesity can make an individual vulnerable to develop OSA, the pathophysiological mechanism for the collapse of the upper airway is unclear. READ MORE
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5. Functional Significance of Multiple Poly(A) Polymerases (PAPs)
Abstract : 3’ end cleavage and polyadenylation are important steps in the maturation of eukaryotic mRNAs. Poly(A) polymerase (PAP), the enzyme catalysing the addition of adenosine residues, exists in multiple isoforms. In this study the functional significance of multiple poly(A) polymerases have been investigated. READ MORE