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Showing result 1 - 5 of 62 swedish dissertations matching the above criteria.
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1. Innate Immune Proteins in a Crustacean Pacifastacus leniusculus
Abstract : Hemocytes (blood cells) are important in the immune defense against pathogens in invertebrates. In crusteacean, the hemocytes and plasma components mount a strong innate immune response against different pathogens including bacteria and virus. READ MORE
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2. Peptidoglycan recognition proteins in Drosophila melanogaster
Abstract : The fruit fly Drosophila melanogaster is an excellent model organism to study the innate immune response, because insects and mammals share conserved features regarding the recognition and destruction of microorganisms and Drosophila is easily accessible to genetic manipulation. In my present study, I identified a new family of pattern recognition molecules for bacterial peptidoglycan in Drosophila, the Peptidoglycan Recognition Proteins (PGRP). READ MORE
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3. Pattern-recognition receptors in airway inflammation
Abstract : Airway inflammation is a defining feature of allergic rhinitis and asthma. Bacterial and viral infections are known to cause exacerbations of both diseases, but knowledge about the mechanisms involved is limited. READ MORE
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4. A Novel Route for Construction of Multipurpose Receptors through Chemical Modification of Glutathione Transferases
Abstract : This thesis describes how the human Alpha class glutathione transferase (GST) A1-1 can be reprogrammed either to function as a multipurpose biosensor for detection of small molecule analytes, or as a handle providing for more efficient protein purification.A novel, user-friendly, and efficient method for site-specific introduction of functional groups into the active site of hGST A1-1 is the platform for these achievements. READ MORE
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5. Recognition by leukocyte formyl peptide receptors. Promiscuous binding or pattern recognition?
Abstract : Neutrophil granulocytes play an important role in the early stages of microbial infection. The neutrophils have to leave the blood stream and migrate out into the tissue where they phagocytose microbes and cell debris from damaged host tissues. READ MORE