Search for dissertations about: "pattern recognition protein"

Showing result 16 - 20 of 63 swedish dissertations containing the words pattern recognition protein.

  1. 16. Structural insights into protein-protein interactions governing regulation in transcription initiation and ubiquitination

    Author : Madhanagopal Anandapadamanaban; Maria Sunnerhagen; Martin Moche; Marie Wahren-Herlenius; Cynthia Wolberger; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Virtually every aspect of the cellular processes in eukaryotes requires that the interactions between protein molecules are well coordinated in different regulatory pathways. Any protein dysfunction involved in these regulatory pathways might lead to various pathological conditions. READ MORE

  2. 17. Free Fatty Acid Receptor 2 - A G protein coupled receptor with unique signaling properties in neutrophils

    Author : Simon Lind; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neutrophils; G protein coupled receptors; Free Fatty Acid Receptor 2; GPR43; Allosteric modulation; Transactivation; Cross-talk; Biased signalling; Functional selectivity;

    Abstract : The overall aim of the PhD thesis was to determine the role of neutrophil pattern recognition receptors in the initiation and resolution of inflammatory processes. Neutrophil pattern recognition receptors such as the formyl peptide receptors (FPRs) and the short free fatty acid receptors (FFARs) belong to the family of G protein coupled receptors (GPCR). READ MORE

  3. 18. Hemolin, a versatile immune protein from the Cecropia moth

    Author : Raul Bettencourt; Kenneth Söderhäll; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Genetics; genetik;

    Abstract : Insects have become useful models for the study of innate immune mechanisms, due to their lack of antibodies and receptors involved in adaptive immune response. However, the molecules and mechanisms involved in primordial immune recognition are still poorly understood. READ MORE

  4. 19. Platelets in inflammation : Role of complement protein C1q, C-reactive proteinand toll-like receptors

    Author : Caroline Skoglund; Torbjörn Bengtsson; Jonas Wetterö; Pentti Tengvall; David Erlinge; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Platelets are proven essential in haemostasis, however, they are now also increasingly recognized as cells with important immunomodulatory properties, e.g. through interaction with leukocytes and several species of bacteria and by release inflammatory mediators upon activation. READ MORE

  5. 20. Ligation-mediated Molecular Analysis of Influenza Subtypes, Splicing and Protein Glycosylation

    Author : Tim Conze; Ulf Landegren; Mats Nilsson; Ola Söderberg; Jörn Glökler; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ligase; proximity ligation; gastric cancer; glycosylation; alternative splicing; avian influenza; padlock probe; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molekylär medicin; Molecular Medicine;

    Abstract : Binder-based assays are employed throughout the life sciences. Powerful signal amplification techniques have enabled detection of very rare molecule species diluted in simple buffers. Unspecific binding of primary binders leads to increased background in more complex samples. READ MORE