Search for dissertations about: "pdt"

Showing result 1 - 5 of 34 swedish dissertations containing the word pdt.

  2. 1. Methods, Instrumentation and Mechanisms for Optical Characterization of Tissue and Treatment of Malignant Tumours

    Author : Sara Pålsson; Atomfysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; temperature; perfusion; PDT; photodynamic therapy; mechanisms; tissue characterization; instrumentation; optical biopsy; fluorescence spectroscopy; spectroscopy techniques; Raman spectroscopy; interstitial photodynamic therapy; photodynamic threshold dose; Atomic and molecular physics; Atom- och molekylärfysik;

    Abstract : In this thesis, different optical methods utilising visible light for characterization of tissue have been developed and evaluated. The feasibility of many of these methods has been demonstrated in the laboratory or in animal experiments. READ MORE

  4. 2. 5-Aminolevulinic acid and derivatives thereof : properties, lipid permeability and enzymatic reactions

    Author : Edvin Erdtman; Leif Eriksson; Tore Brinck; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 5-Aminolevulinic acid; tautomerization; PDT; DFT; MM; QM MM; Porphobilinogen synthase; Uroporphyrinogen III decarboxylase; membrane penetration; enzyme mechanism; Biophysical chemistry; Biofysikalisk kemi; Quantum chemistry; Kvantkemi; Theoretical chemistry; Teoretisk kemi; Fysikalisk kemi; Physical Chemistry; Biochemistry; Biokemi;

    Abstract : 5-aminolevulinic acid (5-ALA) and derivatives thereof are widely usedprodrugs in treatment of pre-malignant skin diseases of the cancer treatmentmethod photodynamic therapy (PDT). The target molecule in 5-ALAPDTis protoporphyrin IX (PpIX), which is synthesized endogenously from5-ALA via the heme pathway in the cell. READ MORE

  5. 3. Exploring nanosystems for biomedical applications focusing on photodynamic therapy and drug delivery

    Author : Vladimir Kirejev; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Photodynamic therapy; PDT enhancement; Nitric oxide; NO-based PDT; Targeted drug delivery; Galectin-3; mTHPP; Cyclodextrin; CD-mTHPP conjugate; PpIX AuNP combination; Two-photon microscopy; FLIM; Cell phototoxicity; Ex vivo skin;

    Abstract : The increasing incidences of cancer and related deaths call for the development of new and improved treatment modalities. Photodynamic therapy (PDT) today is an alternative to conventional treatments, but has limitations. This thesis explores different nanosystems with aim to improve PDT focusing on spectroscopic and ex vivo studies. READ MORE

  6. 4. Primary and Secondary Outcomes from a Double Randomized Clinical Preference Trial of two Panic-Focused Psychotherapies

    Author : Thomas Nilsson; Institutionen för psykologi; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Paniksyndrom; Kognitiv beteendeterapi KBT ; Psykodynamisk terapi PDT ; Arbetsförmåga; Termination setback; Panic Disorder; Cognitive Behavioural Therapy CBT ; Psychodynamic Therapy PDT ; Work Ability; Termination Setback;

    Abstract : Approximately 2-3% of adults in Sweden will experience unexpected panic attacks that cause them to develop fears of future attacks and to alter their lives, defined as Panic Disorder with or without Agoraphobia (PD/A). The condition often onsets in late adolescence or early adulthood, with high levels of psychiatric comorbidity, social difficulties, diminished study and work ability, an elevated risk for substance use, health problems, and mortality. READ MORE

  7. 5. Photodynamic therapy and laser-based diagnostic studies of malignant tumours

    Author : Ingrid Wang; Medicinskt lasercentrum; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protoporphyrin IX PpIX ; delta -aminolevulinic acid ALA ; photosensitizer; basal cell carcinoma BCC ; Photodynamic therapy PDT ; laser-induced fluorescence LIF ; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : Two non-thermal regimens of light interaction with biological tissue, that are in a natural way connected, are discussed in the present thesis. These are photodynamic therapy (PDT) for the treatment of malignant tumours and laser-induced fluorescence (LIF) for tissue characterization. READ MORE