Search for dissertations about: "pediatric drug safety"
Showing result 1 - 5 of 10 swedish dissertations containing the words pediatric drug safety.
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1. Pharmacoepidemiologic studies of drug safety in pediatric chronic inflammatory disease
Abstract : Safety evidence for use of pharmaceutical drugs in children, including treatments for serious conditions such as chronic inflammatory diseases, is generally scarce. Off-label use is common and clinicians need to rely on evidence from adults when prescribing to children. READ MORE
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2. Off-label drug use, medication errors and adverse drug events : among Swedish pediatric inpatients
Abstract : Background: In pediatrics, treatment with drugs is an important and fully integrated part of everyday medical practice. However, authorized drugs specified to be used in children are often lacking which leads to off-label use, i.e. outside of approved product monographs. READ MORE
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3. Drug administration and blood sampling for pharmacokinetic studies in pediatric cancer patients
Abstract : This thesis focuses on drug administration and blood sampling for pharmacokinetic studies in pediatric cancer patients. Only about one third of the drugs used to treat children have been adequately tested with sufficient information regarding safety and efficacy for pediatric patients. READ MORE
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4. Clonidine in pediatric anesthesia : aspects on population pharmacokinetics, nasal administration and safety
Abstract : Clonidine is widely use as premedication in pediatric patients and has many beneficial effects in the perioperative period. The introduction of population pharmacokinetics in the 1980s has proven useful when performing pharmacokinetic studies in children to circumvent previous limitations with traditional pharmacokinetics. READ MORE
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5. Anticancer drug treatment in pediatric patients : studies on optimizing dosage and on parental guidance for improved drug handling at home
Abstract : Background: Every year about 370 children are diagnosed with cancer in Sweden. The treatment includes both inpatient and outpatient care with anticancer drugs. At the clinic, the optimal anticancer drug dosage is usually derived from the patient’s body surface area (BSA). READ MORE