Search for dissertations about: "pedro"

Showing result 1 - 5 of 85 swedish dissertations containing the word pedro.

  2. 1. Molecular basis for the mechanism of action and resistance to artemisinin combination therapy in Plasmodium falciparum

    Author : Pedro Ferreira; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Plasmodium falciparum;

    Abstract : Malaria, caused by the Plasmodium falciparum parasite, remains a leading cause of death among children in Africa. To improve treatment efficacy and delay development and spread of antimalarial drug resistance artemisinin artemisinin-based combination therapy (ACT) is now globally recommended as first-line treatment of uncomplicated P. READ MORE

  4. 2. Nucleic acid in gene delivery and gene regulation

    Author : Pedro Moreno; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The concept of gene therapy, initially attributed to a technology that would allow the correction of inherited genetic disease, has evolved over the years. The realization of the immense technical hurdles to achieve genetic correction led to a broadening of the concept now including the transfer of genetic material whose expression will counteract, mitigate or revert a disease phenotype. READ MORE

  5. 3. Reconfiguration Methodology to improve the agility and sustainability of Plug and Produce Systems

    Author : Pedro Neves; Mauro Onori; Åsa Fasth Berglund; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Production Engineering; Industriell produktion;

    Abstract : The emergence of globalisation, market turbulence and sustainability requirements is challenging production companies to devise new strategies to offer large product diversity, keep low inventories, and timely produce small batches of customised and personalised products. Agile shop-floors that can be promptly deployed and re-configured with minimum integration and programming efforts are perceived as a promising strategy to tackle this problem. READ MORE

  6. 4. On the fluid mechanics of electrochemical coating and spray painting

    Author : Pedro Olivas; KTH; []
    Keywords : mass transfer; electrochemical coating; ion transport; forced convection; diffusion; magnetoelectrolysis; electrolyte; limiting current; numerical simulation;

    Abstract : Finite-volume methods have been used for modeling of fluidflows involved in forced convection electrochemical coating androtating spray painting systems. Electrodeposition on a singlecircular cylinder under forced convection for Reynolds numbers10 and 200 was simulated. READ MORE

  7. 5. Development and application of new chiral -amino alcohols in synthesis and catalysis : Use of 2-azanorboryl-3-methanols as common intermediates in synthesis and catalysis

    Author : Pedro Pinho; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Asymmetric synthesis; hetero-Diels-Alder reactions; chiral cyclopentyl-amines; chiral ligands and catalysts; amino alcohols; asymmetric reductions; ruthenium transfer hydrogenation; oxazaborolidines; asymmetric additions; dialkylzinc reagents; Kemi; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Abstract : The development and application of unnatural amino alcohols,prepared via hetero-Diels-Alder reactions,in synthesis and catalysis is described.The studies are concerned with the [i]scope of the hetero-Diels-Alder reaction and preparation of important intermediates in the synthesis of antiviral agents,[ii ]application of amino alcohols in the ruthenium transfer hydrogenation of ketones,[iii ]use of similar precursors in the in situ generation of oxazaborolidines for reduction of ketones,and [iv] development and application of new chiral auxiliaries for dialkylzinc additions to activated imines, respectively. READ MORE