Search for dissertations about: "peptide-lipid interaction"
Showing result 1 - 5 of 6 swedish dissertations containing the words peptide-lipid interaction.
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1. NMR Investigations of Peptide-Membrane Interactions, Modulation of Peptide-Lipid Interaction as a Switch in Signaling across the Lipid Bilayer
Abstract : The complexity of multi cellular organisms demands systems that facilitate communicationbetween cells. The neurons in our brains for instance are specialized in this cell-cellcommunication. READ MORE
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2. Aggregation behavior and peptide-lipid interaction in an amyloid model system
Abstract : Proteins constitute a major component of living cells and are essential to their function. Sometimes proteins misfold or aggregate in abnormal ways, which can give rise to diseases. Amyloids are a special type of highly ordered protein aggregates made of long intermolecular beta-sheets stacked into fibrils. READ MORE
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3. Membrane Induced Structure in Transmembrane Signaling Proteins and Peptides : Peptide–Lipid Interactions Studied by Spectroscopic Methods
Abstract : Biological membranes, defining the boundary of cells and eukaryotic organelles, are mainly composed of lipids and membrane proteins. Interactions between these lipids and proteins are needed to preserve the tight seal of the membrane, but also to induce structure for proper function in many membrane proteins. READ MORE
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4. Biological membrane interfaces involved in diseases : a biophysical study
Abstract : Interactions between peptides and biological lipid membranes play a crucial role in many cellular processes such as in the mechanism behind Alzheimer’s disease where amyloid-beta peptide (Abeta)is thought to be a key component. The initial step of binding between a surface active peptide and its target membrane or membrane receptor can involve a non specific electrostatic association where positively charged amino acid residues and a negatively charged membrane surface interact. READ MORE
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5. Membrane mediated aggregation of amyloid-β protein : a potential key event in Alzheimer's disease
Abstract : The pathogenesis of Alzheimer’s disease (AD), the most common senile dementia, is a complex process. A crucial event in AD is the aggregation of amyloid-β protein (Aβ), a cleavage product from the Amyloid Precursor Protein (APP). READ MORE