Search for dissertations about: "peptide-phage display"
Showing result 1 - 5 of 8 swedish dissertations containing the words peptide-phage display.
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1. Using peptide-phage display to capture conditional motif-based interactions
Abstract : This thesis explores the world of conditional protein-protein interactions using combinatorial peptide-phage display and proteomic peptide-phage display (ProP-PD). Large parts of proteins in the human proteome do not fold in to well-defined structures instead they are intrinsically disordered. READ MORE
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2. Identification of SLiMs: Mapping and characterizing motif-based protein interactions
Abstract : During the last twenty years it has become evident that about 35-40% of amino acids in the proteome are in regions that have evolved to remain unstructured. These intrinsically disordered regions contain short linear motifs (SLiMs), which serve as docking sites for protein-protein interactions. READ MORE
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3. Evolution and viral mimicry of short linear motif-mediated interactions
Abstract : Proteins are one of the most fundamental building blocks of life and their interactions regulate every cellular process. Historically they have been conceptualized as predominantly folded entities with well-defined secondary and tertiary structures. READ MORE
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4. Bacteriophages and cryogels: A new efficient tool in bioseparation
Abstract : Abstract Due to developments in the last decades in the field of protein production, new technologies for bio-separation have evolved. Especially in the field of affinity chromatography, the search for new ligands is of great interest. Besides the antibodies used as affinity ligands, synthetic ligands were introduced. READ MORE
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5. Diving into short linear motifs : Large-scale identification of endogenous and host-pathogen protein-protein interactions and further characterized by deep mutational scanning
Abstract : Short linear motifs (SLiMs) are protein-protein interaction sites that play an essential role in distinct cellular processes. Those interactions are challenging to capture by common high-throughput methods. READ MORE