Search for dissertations about: "peptidomimetics"
Showing result 21 - 25 of 27 swedish dissertations containing the word peptidomimetics.
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21. Design and Synthesis of 2,3,6,8-Tetrasubstituted Chromone Derivatives by Pd-Catalyzed Copuling Reactions. Potential Scaffolds for Peptidomimetics
Abstract : .... READ MORE
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22. The Impact of the Neuropeptide Substance P (SP) Fragment SP1-7 on Chronic Neuropathic Pain
Abstract : There is an unmet medical need for the efficient treatment of neuropathic pain, a condition that affects approximately 10% of the population worldwide. Current therapies need to be improved due to the associated side effects and lack of response in many patients. READ MORE
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23. Synthesis of Potential Inhibitors Against HIV
Abstract : This thesis describes the syntheses of various potential inhibitors of HIV, e.g. some 3´-hydroxymethyl-substituted carbocyclic nucleoside analogues as reverse transcriptase inhibitors and some symmetry-based peptidomimetics as protease inhibitors. READ MORE
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24. Design, Synthesis, and Evaluation of Functionalized Chroman-4-one and Chromone Derivatives. Somatostatin receptor agonists and Sirt2 inhibitors
Abstract : Peptides are involved in many physiological processes such as regulation of blood-pressure, food intake, pain transmission and blood-glucose levels. They consist of amino acids that are connected through amide bonds which make peptides hydrophilic and conformationally flexible. READ MORE
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25. Neutrophil Function and Signaling Induced by Ligands for the Formyl Peptide Receptor 2
Abstract : Neutrophil pattern recognition receptors belonging to the G-protein coupled receptor (GPCR) family play a role in the processes of initiation as well as resolution of inflammatory processes. Formyl peptide receptor 2 (FPR2) in neutrophils is such a receptor and plays an important role in inflammation. READ MORE