Search for dissertations about: "perforin"

Showing result 21 - 25 of 47 swedish dissertations containing the word perforin.

  2. 21. Neoehrlichiosis - latent infection of endothelium and immune defense

    Author : Linda Wass; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neoehrlichia mikurensis; neoehrlichiosis; human; infectious disease; endothelial cell; T cell;

    Abstract : This thesis is a study of the tick-borne pathogen Neoehrlichia (N.) mikurensis that causes the infectious disease neoehrlichiosis in humans. The disease affects both individuals with competent and suppressed immune defense with the majority of the affected being immunosuppressed. READ MORE

  4. 22. Arbetsterapeutisk träning efter höftfraktur : aktivitetsförmåga och hälsorelaterad livskvalitet

    Author : Birgit Hagsten; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hip fractures constitute a common injury leading to reduced functional abilities. In a randomised trial we investigated whether an early, individualised occupational therapy training programme had any effects on patients' (> 65 years) post-operative ability to perform activities of daily life (AM), and instrumental activities of daily life (IADL), as well as self-assessments of their health-related quality of life (HRQL). READ MORE

  5. 23. Hantaviruses : shedding, stability and induction of apoptosis

    Author : Jonas Hardestam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hantaviruses are spread and maintained in different rodent and insectivore species worldwide. Humans are believed to be infected mainly by inhalation of aerosolized contaminated rodent excreta. READ MORE

  6. 24. Human cytomegalovirus immune evasion strategies

    Author : Jenny Odeberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Human cytomegalovirus (HCMV) is a member of the herpes virus family. HCMV is a ubiquitous pathogen, causing severe morbidity and mortality in immunocompromised patients, and is a major factor in congenital birth defects. READ MORE

  7. 25. Early induced immune responses : regulation of dendritic cell and NK cell functions

    Author : Robert Wallin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Dendritic cell; Natural killer cell; Cytoskeleton; cAMP; cytotoxicity;

    Abstract : The evolution of the advanced vertebrate adaptive immune system has required co-evolution of sophisticated immune regulating systems that determine immune class of cytokines, antibodies as well as effector mechanisms used by killer cells. The co-ordination of these responses are likely to be carried out by dendritic cells (DC) under the influence of the tissue cells and innate immune cells resident in the tissue from where the DC originates. READ MORE