Search for dissertations about: "pericytes"

Showing result 1 - 5 of 51 swedish dissertations containing the word pericytes.

  1. 1. Functions of Pericytes in Ischemic Stroke

    University dissertation from Lund University: Faculty of Medicine

    Author : Michaela Roth; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; Pericytes; RGS5; Blood-brain barrier; vascular remodelling; scar formation;

    Abstract : Ischemic stroke remains one of the leading causes of death and disability worldwide, and its burden is predicted to further increase due to the aging population. The only available treatments, thrombolysis or thrombectomy, can only be applied within a limited time window after stroke onset, and thus are applicable only to a small proportion of stroke patients. READ MORE

  2. 2. Pericytes in Neurodegeneration

    University dissertation from Lund University: Faculty of Medicine

    Author : Thomas Padel; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pericyte; Parkinson disease; Huntington Disease; PDGF-BB; RGS5;

    Abstract : .... READ MORE

  3. 3. The Impact of Amyloid Peptides on Pericytes in Alzheimer's Disease

    University dissertation from Lund University: Faculty of Medicine

    Author : Nina Schultz; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pericytes; Alzheimer s disease; Amyloid peptides; IAPP; Amyloid beta 1-42; Amyloid beta 1-40; Cell death; NG2; Retina; Hippocampus;

    Abstract : .... READ MORE

  4. 4. Pericyte Influence on Drug Delivery Across the Blood-Brain Barrier Implications for Therapy of Neurodegenerative Diseases

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Nebojsa Mihajlica; Uppsala universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; pericytes; pericyte-deficiency; pharmacokinetics; small-molecular drugs; drug distribution; transporters; P-glycoprotein; tyrosine kinase inhibitors; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy;

    Abstract : The blood-brain barrier (BBB) represents a complex interface between the brain parenchyma and systemic blood circulation, strictly controlling exchange of substances between the two sites. Pericytes are mural cells located on the abluminal membrane of the brain endothelium, involved in BBB formation and maintenance. READ MORE

  5. 5. Conditional targeting of the PDGF-B gene

    University dissertation from Göteborg

    Author : Maria Enge; Göteborgs universitet.; Gothenburg University.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gene targeting; Cre loxP; PDGF; pericytes; diabetic retinopathy; brain injury; neurons;

    Abstract : Platelet derived growth factors (PDGF) are known as mitogens for fibroblasts, smooth muscle cells (SMC) and glia cells in culture. Previous in vivo analyses have shown that PDGF-B is necessary for normal embryonic development and life after birth, but the relative importance of the various cellular sources of PDGF-B during development has not been clarified. READ MORE