Search for dissertations about: "pericytes"

Showing result 16 - 20 of 59 swedish dissertations containing the word pericytes.

  2. 16. A functional genomics approach to PDGF and pericyte biology

    Author : Cecilia Bondjers; Göteborgs universitet; []
    Keywords : PDGF; hair follicle; skin; testis; epithelial-mesenchymal interaction; microarray; pericyte; transgenic mouse;

    Abstract : The rapid expansion of genome sequence data demands for increased efforts and speed concerning functional analysis of gene products. Two approaches to such analysis, namely transgenic technologies and analysis of gene expression have successfully been used to study functions of gene products in complex organisms, such as mammals. READ MORE

  4. 17. Exploring the functional heterogeneity of the tumor microenvironment

    Author : Eliane Cortez; Avdelningen för translationell cancerforskning; []
    Keywords : ;

    Abstract : Tumors are complex entities, composed of different functional populations of malignant and stromal cells. There is an emerging importance to understand previously unmapped communication routes between different cell and non-cell compartments of the tumor microenvironment. READ MORE

  5. 18. Mechanisms of tumor microenvironment in promoting metastasis

    Author : Patrik Andersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tumor tissues contain diverse cell populations that relentlessly cross-communicate with each other in the tumor microenvironment. In addition to malignant cells, infiltration of other host cells including inflammatory cells, fibroblasts, and cells in the vessel walls in tumors significantly contribute to tumor growth and metastasis. READ MORE

  6. 19. To scar or not to scar : origin and function of fibrotic tissue in the central nervous system

    Author : David Oliveira Dias; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : After injury, the adult mammalian central nervous system lacks long-distance axon regeneration, and insufficient repair results in the formation of a multicellular and compartmentalized scar. A great body of work has been dedicated to the study of the glial component of the scar, while the fibrotic lesion core has received less attention. READ MORE

  7. 20. Expression profiling of blood vessels in pericyte deficiency and diabetes

    Author : Jenny Norlin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The kidney glomerulus is essential for the filtration of waste products from the blood into the urine and in controlling the volume and composition of body fluids. Injury to the glomerulus can lead to altered glomerular filtration rate, proteinuria, thickening of the glomerular basement membrane (GBM) and accumulation of mesangial cell matrix. READ MORE