Search for dissertations about: "peripheral nerve injury"

Showing result 6 - 10 of 97 swedish dissertations containing the words peripheral nerve injury.

2. 6. An exploration of the mechanisms behind peripheral nerve injury

   Author : Rebecca Wiberg; Liudmila Novikova; Paul Kingham; Ash Mosahebi; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peripheral nerve injury; target organ; spinal motoneurons; primary sensory neurons; degeneration; anatomi; Human Anatomy;

   Abstract : Despite surgical innovation, the sensory and motor outcome after peripheral nerve injury is incomplete. In this thesis, the biological pathways potentially responsible for the poor functional recoveries were investigated in both the distal nerve stump/target organ, spinal motoneurons and dorsal root ganglia (DRG). READ MORE

4. 7. Neuroprotection and axonal regeneration after peripheral nerve injury

   Author : Dag Welin; Lev N. Novikov; Lars B. Dahlin; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dorsal root ganglion; Motoneuron; Axonal reaction; Peripheral nerve injury; Nerve regeneration; N-acetylcysteine; Hand surgery; Handkirurgi; Anatomy; Anatomi; anatomi; Human Anatomy; handkirurgi; hand surgery;

   Abstract : Following microsurgical reconstruction of injured peripheral nerves, severed axons are able to undergo spontaneous regeneration. However, the functional result is always unsatisfactory with poor sensory recovery and reduced motor function. READ MORE

5. 8. The sensational hand. Clinical assessment after nerve repair

   Author : Birgitta Rosén; Malmö Handkirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; substitution of senses; artificial sensibility; reliability; validity; diagnose-specific; documentation; assessment; longitudinal; functional outcome; hand; sensibility; ulnar nerve; nerve repair; median nerve; brain plasticity; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

   Abstract : Following the transection and repair of major nerve trunks in the forearm, the functional outcome is influenced by mechanisms in the peripheral, as well as in the central nervous system. In the present thesis the interest is focused on assessment of the outcome after nerve repair, central nervous factors influencing the outcome, and sense substitution to compensate for sensory loss. READ MORE

6. 9. The use of adipose derived stem cells in spinal cord and peripheral nerve repair

   Author : Mallappa K Kolar; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spinal cord injury; peripheral nerve injury; adipose derived stem cells; regeneration; neurotrophic factor; angiogenic factor;

   Abstract : Clinically, injuries affecting the spinal cord or peripheral nerves can leave those affected with severe disability and, at present, there are limited options for treatment. Peripheral nerve injury with a significant gap between the proximal and distal stumps is currently treated with autologous nerve grafting but this is limited by availability of donor nerve and has associated morbidities. READ MORE

7. 10. Regulation of Injury Induced Schwann Cell Proliferation Schwann Cell Proliferation

   Author : Åsa Fex Svenningsen; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; estrogen; signal transduction; insulin like growth-factors; Schwann cell; peripheral; nerve regeneration; Djurfysiologi; Animal physiology; progesterone;

   Abstract : The purpose of this study was to investigate injury induced proliferation of Schwann cells with emphasis of the effects of the insulin-like growth factors (IGF-I and IGF-II) and the sex hormones progesterone and estrogen. Proliferation, measured as [3H] thymidine incorporation, was studied in cultured segments of the rat sciatic nerve or through the use of the thymidine analogue bromo- deoxy-uridine (BrdU) in combination with immunocytochemistry. READ MORE