Search for dissertations about: "peripheral neuropathy"

Showing result 21 - 25 of 49 swedish dissertations containing the words peripheral neuropathy.

2. 21. Neurons and glia in the peripheral nervous system : interactions in health and disease

   Author : Filipa Bouçanova; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The peripheral nervous system (PNS) is composed of nerves and ganglia that connect the brain and the spinal cord (the central nervous system, CNS) to the outside world. The nerves contain the extensions (axons) of both sensory and motor neurons, which allow us to detect and respond to different stimuli. READ MORE

4. 22. A pathway for pleasant touch: linking peripheral receptors to central processing and hedonic experience

   Author : Line Sofie Löken; Göteborgs universitet; []
   Keywords : pleasant; touch; microneurography; human; CT afferent; unmyelinated;

   Abstract : This thesis investigates the mechanisms underpinning pleasant touch, describes a pathway from peripheral nerve endings in the skin to the insular cortex, and relates these findings to the subjective hedonic experience of touch. In Paper I, the relationship between primary afferent encoding and perception of pleasantness was investigated by combining microneurography recordings from human mechanoreceptors with psychophysical measurements during soft brush stroking at 6 different velocities between 0. READ MORE

5. 23. The role of adenosine and its receptor subtypes in nociception and neuropathic pain

   Author : Weiping Wu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Adenosine; adenosine receptors; antinociception; caffeine; knock-out mouse; neuropathy; morphine; R-PIA;

   Abstract : As neurotransmitter/modulator, adenosine plays an important role in nociceptive processing. Adenosine receptors are G-protein coupled and four receptor subtypes, A1, A2A, A2B and A3 have been identified. It is well established that adenosine and its receptor agonists produce primarily antinociceptive effect in animals and humans. READ MORE

6. 24. Studies in sporadic inclusion body myositis

   Author : Snjólaug Arnardóttir; Karolinska Institutet; Karolinska Institutet; []
   Keywords : s-IBM; muscle fibre regeneration; cytoskeleton; IVIg; muscle inflammtion; cytokine; training; sensibility; neuropathy ;

   Abstract : Aims: The general aims of the present study were to increase the understanding of the disease process in s-lBM by analysing the cytoskeletal structure in muscle fibres and their regeneration potential; and also to evaluate sensory function in patients with s-IBM to test the hypothesis of an associated neurogenic component or a concomitant neuropathy in s-IBM; and to evaluate therapeutic options by analysing the effect of IVIg treatment on the muscle inflammation; and to evaluate the effect of training on muscle function and muscle inflammation. Patients: Twenty-six patients with the diagnosis of s41BM participated in these studies. READ MORE

7. 25. Diabetic osteopathy : a study in the rat

   Author : Tashfeen Ahmad; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Diabetes mellitus type 2; Goto-Kakizaki rat; bone mineral density; insulin-like growth factor-I; insulin-like growth factor binding protein 1; insulin-like growth factor binding protein 4; peripheral neuropathy; substance P; calcitonin gene-related peptide; neuropeptide Y; Diabetes mellitus type 2;

   Abstract : The present study on non-obese Goto-Kakizaki (GK) rats with type-2 diabetes and neuropathy was an attempt to describe and define pertinent features of diabetic osteopathy. Altogether, the study included 33 GK rats aged 12 and 20 months, and 36 age-matched Wistar rats as controls. READ MORE