Search for dissertations about: "perivascular tissue"

Showing result 16 - 20 of 28 swedish dissertations containing the words perivascular tissue.

  2. 16. The role of the lymph node stroma in cancer and aging

    Author : Tove Bekkhus; Maria H. Ulvmar; Timothy P. Padera; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lymph node; Stroma; High endothelial venule HEV ; Lymphatic endothelial cells LECs ; Breast cancer; Metastasis; Lipomatosis; Medicinsk vetenskap; Medical Science;

    Abstract : The function of the lymph node (LN) stroma is crucial for the induction of an adaptive immune response. The stroma includes lymphatic vessels, high endothelial venules (HEVs) and mesenchymal cells (MCs). In this thesis, I have been investigating the role of the LN stroma in cancer and aging. READ MORE

  4. 17. Tumour microenvironment in serous ovarian cancer

    Author : Sara Corvigno; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Ovarian cancer is the seventh most common malignancy in women worldwide and the most lethal gynaecological malignancy in developed countries. The epithelial subtype is divided in five main histologic groups, of which the high-grade serous is the most common subtype. READ MORE

  5. 18. Functions of Pericytes in Ischemic Stroke

    Author : Michaela Roth; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; Pericytes; RGS5; Blood-brain barrier; vascular remodelling; scar formation;

    Abstract : Ischemic stroke remains one of the leading causes of death and disability worldwide, and its burden is predicted to further increase due to the aging population. The only available treatments, thrombolysis or thrombectomy, can only be applied within a limited time window after stroke onset, and thus are applicable only to a small proportion of stroke patients. READ MORE

  6. 19. Chemokine receptor expression and function in experimental autoimmune neuroinflammation

    Author : Sana Eltayeb; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Neuroinflammatory lesions in the central nervous system (CNS) are characterized by the presence of leukocytes, mainly monocytes/macrophages, derived from the systemic compartment. We believe CC inflammatory chemokine receptors (CkRs), CCR1, CCR2 and CCR5 are prerequisite for controlling the migration of monocytes/macrophages into inflammatory foci. READ MORE

  7. 20. Stem cell based therapy of malignant brain tumors

    Author : Daniel Bexell; Sektion IV; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; pericyte; mesenchymal stem cell; neuroblast; subventricular zone; cancer stem cell; rat; glioma; cancer;

    Abstract : Malignant brain tumor is a highly invasive and vascularized cancer. Current forms of therapy are not curative and can, at best, prolong survival for patients with this disease. The mean survival is only around 15 months. READ MORE