Search for dissertations about: "permeabilized cells"

Showing result 1 - 5 of 19 swedish dissertations containing the words permeabilized cells.

  2. 1. The significance of Ca2+ in the regulation of insulin release : studies comprising intact and permeabilized pancreatic ß-cells

    Author : Thomas Nilsson; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  4. 2. Interactions of the Cell-Penetrating Peptide Penetratin with Model Membranes and Live Cells

    Author : Daniel Persson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; antisense; antennapedia homeodomain; delivery vector; cell-penetrating peptide; protein transduction; uptake; membrane translocation; penetratin; confocal microscopy; vesicle;

    Abstract : The delivery of large, hydrophilic molecules, such as proteins and oligonucleotides, to the cytoplasm and nucleus of cells is problematic due to their generally low plasma membrane permeability. With the identification of a number of cell-penetrating peptides, capable of mediating non-endocytotic, intracellular delivery of macromolecular cargos, this obstacle now seems surmountable. READ MORE

  5. 3. Regulation of Phospholipase C and Plasma Membrane Phosphatidylinositol 4,5-bisphosphate in Insulin-Secreting Cells

    Author : Sophia Thore; Anders Tengholm; Erik Gylfe; Peter Jones; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; PLC; PIP2; insulin-secreting cell; Ca2 ; evanescent wave microscopy; phosphoinositide kinase; ATP ADP ratio; Cellbiologi; Cell biology; Cellbiologi;

    Abstract : The membrane phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) is an important signaling molecule as substrate for the phospholipase C (PLC)-catalyzed formation of inositol 1,4,5-trisphosphate (IP3) and diacylglycerol, and by directly regulating e.g. ion-channels, the cytoskeleton and vesicle trafficking in various types of cells. READ MORE

  6. 4. Macromolecular interactions, Consequences on carbohydrate metabolism

    Author : Sandra Matic; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; macromolecular interactions; sucrose synthase; macromolecular crowding; cytoskeleton; BY-2 tobacco cells; alamethicin; aqueous polymer two-phase partitioning;

    Abstract : Most cells are crowded with solutes, enzymes, nucleic acids, structural proteins and membranes. Crowding promotes macromolecular interactions and determines major properties of the cellular environment such as viscosity, diffusion and inhomogeneity. READ MORE

  7. 5. Expression, recognition and usage of laminin-8 (a4b1g1, Lm-411) by monocytes and neutrophils

    Author : Zenebech Wondimu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Basement membrane; laminins; myeloid cells; extravasation; migration.;

    Abstract : Laminins (LNs) are a family of large alphabetagamma heterotrimeric glycoproteins found in all basement membranes (BMs). They are expressed in a tissue- and developmental stagespecific manner and implicated in vital cellular functions, including cell adhesion, migration and signaling. READ MORE