Search for dissertations about: "pernilla"

Showing result 16 - 20 of 201 swedish dissertations containing the word pernilla.

  2. 16. Afferent input to midbrain dopamine neurones and its modulation : an electrophysiological study i vitro

    Author : Pernilla Grillner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : dopamine neurones; synaptic transmission; NMDA receptors; L-type Ca2 channels; presynaptic inhibition; metabotropic glutamate receptors; muscarine; nicotine;

    Abstract : Dopamine (DA) neurones of the ventral mesencephalon are involved in the control of reward related behaviour, cognitive functions and motor performances, and provide a critical site of action for major categories of neuropsychiatric drugs, such as antipsychotic agents, dependence producing drugs and anti-Parkinson medication. The midbrain DA neurones are mainly located in the substantia nigra pars compacta (SNPC) and the ventral tegmental area (VTA). READ MORE

  4. 17. Genetic adaptation to soil acidification in four grasses

    Author : Pernilla Göransson; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Växtekologi; Plant ecology; Deschampsia flexuosa; Deschampsia cespitosa; Elymus caninus; Poa nemoralis; arbuscular mycorrhiza; stress; tolerance; genetic variation; local adaptation; Al; Soil acidification; pH;

    Abstract : Soil acidification has become a source of serious concern in many parts of the world. In southern Sweden, the deposition of acidifying substances, such as nitrogen and sulphur compounds, has decreased the mean pH of forest soils by almost one unit since the 1950s. READ MORE

  5. 18. Well-being among the very old : a survey on a sample aged 90 years and above

    Author : Pernilla Hillerås; Kim Lützén; Sophiahemmet Högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : This thesis examines well-being among the very old and the factors believed to influence the three components of well-being called life satisfaction, positive affect and negative affect. It also examines activity patterns, the factors related to activity and the consequences of different types of activity for well-being. READ MORE

  6. 19. Genetic studies of susceptibility to diabetes mellitus with emphasis on type 1 diabetes

    Author : Pernilla Holm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Diabetes mellitus is a common multifactorial disease that needs lifelong treatment of insulin and/or oral treatment to prevent hyperglycaemia. Despite treatment, patients with diabetes, still suffer from severe complications later in life. READ MORE

  7. 20. Generation and evolution of human antibody fragments - The CDR shuffling approach

    Author : Pernilla Jirholt; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; Biokemisk teknik; Biokemi; Biochemistry; Biochemical technology; Metabolism; Immunologi; serologi;

    Abstract : Antibodies are important proteins participating in a number of reactions to protect us from harmful diseases. Apart from this important function, they are also useful in different technical and medical applications. This, however, relies on our possibility to produce antibodies in vitro. READ MORE