Search for dissertations about: "pet tracer"

Showing result 21 - 25 of 89 swedish dissertations containing the words pet tracer.

2. 21. Quantitative cardiac 15O-water PET : Assessment of left-ventricular function, remodeling, and impact of patient motion

   Author : Jonny Nordström; Mark Lubberink; Jens Sörensen; Hendrik J Harms; Stephan Nekolla; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; positron emission tomography PET ; 15O-water; myocardial blood flow; cardiac remodeling; patient motion;

   Abstract : International guidelines advocate the use of noninvasive cardiac imaging as the initial diagnostic test for coronary artery disease, the global leading cause of death according to the world health organization. Within the wide spectrum of cardiac imaging, 15O-water PET is the gold standard for noninvasive quantification of myocardial blood flow (MBF). READ MORE

4. 22. Exploring Palladium-Mediated 11C/12C-Carbonylation Reactions : PET Tracer Development Targeting the Vesicular Acetylcholine Transporter

   Author : Sara Roslin; Mats Larhed; Gunnar Antoni; Jonas Eriksson; Luke Odell; Victor Pike; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Carbonylation; palladium; carbon-11; radiochemistry; positron emission tomography; vesicular acetylcholine transporter; vesamicol; alkyl halide; oxidative carbonylation; acylamidine; oxadiazole; heterocycle; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : The work presented herein describes the utilization and exploration of palladium-mediated incorporations of carbon monoxide and/or [11C]carbon monoxide into compounds and structural motifs with biological relevance.The first part of the thesis describes the design, synthesis and 11C-labeling of prospective PET tracers for the vesicular acetylcholine transporter (VAChT), a target affected in several neurodegenerative diseases. READ MORE

5. 23. Towards Clinical Implementation of Dynamic Positron Emission Tomography in Neurodegenerative Diseases

   Author : My Jonasson; Mark Lubberink; Lieuwe Appel; Jens Sörensen; Michel Koole; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Positron emission tomography; PET; Molecular imaging; Quantification; Kinetic modelling; Parametric images; Alzheimer’s disease; Parkinson’s disease; Radiology; Radiologi;

   Abstract : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common neurodegenerative disorders worldwide. Positron emission tomography (PET), together with suitable biomarkers, can aid in the clin-ical evaluation as well as in research investigations of these diseases. READ MORE

6. 24. Abdominal Aortic Aneurysm : Molecular Imaging Studies of Pathophysiology

   Author : Gustaf Tegler; Anders Wanhainen; Martin Björck; Jens Sörensen; Lars Norgren; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abdominal aortic aneurysm; AAA; Positron emission tomography; PET; Molecular Imaging; Pathophysiology; Autoradiography; Angiogenesis; integrin alphaVbeta3; FDG; 18F-FDG; 11C-PK11195; 11C-D-deprenyl; [18F]fluciclatide; Fluciclatide; Bukaortaaneurysm; Molekylär bilddiagnostik; Patofysiologi; PET; Autoradiografi; Angiogenes; Surgery; Kirurgi; Medicinsk radiofysik; Medical Radiophysics;

   Abstract : The pathological process behind abdominal aortic aneurysm (AAA) formation is poorly understood and difficult to study. The aim of the thesis was to study the pathophysiology of AAA formation with positron emission tomography (PET) technology, a molecular imaging technique, allowing in vivo studies of pathophysiological changes. READ MORE

7. 25. Computed tomography, magnetic resonance imaging and positron emission tomography in non-Hodgkin's lymphoma

   Author : Miriam Rodriguez; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; NHL; CT; MRI; PET; malignancy grade; prognosis; residual mass; Onkologi; Oncology; Onkologi; diagnostisk radiologi; Diagnostic Radiology;

   Abstract : Certain aspects of the use of computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) were evaluated in patients with non-Hodgkin'slymphoma (NHL) with the aim of improving the management of these patients.Subjective evaluation of the tumor pattern on CT images, and quantification of tracer uptake using 11C methionine (11C Met) and [18F] fluorodeoxyglucose (18FDG) PET in patients with NHL, were performed to determine their relations to malignancy grade. READ MORE