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Showing result 1 - 5 of 204 swedish dissertations matching the above criteria.

  2. 1. Resistance to phagocytosis in Streptococcus pyogenes

    Author : Fredric Carlsson; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infektioner; Infections; Medicine human and vertebrates ; Medicin människa och djur ; phagocytosis; innate immunity; complement; Streptococcus pyogenes; M protein;

    Abstract : Phagocytosis of Streptococcus pyogenes is complement dependent. However, the cell wall-associated M protein, which exists in >100 different serotypes (M types), enables the bacteria to evade phagocytosis. READ MORE

  4. 2. Mechanisms of phagocytosis resistance in Streptococcus pyogenes

    Author : Heike Kotarsky; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; fibrinogen; FHL-1; Factor H; M protein; Streptococcus pyogenes; phagocytosis;

    Abstract : A distinguishing feature of Streptococcus pyogenes (GAS) is their ability to resist phagocytosis in whole human blood in the absence of type-specific antibodies, a property that is dependent on the expression of the surface associated M proteins. A common characteristic of M proteins is their interaction with a variety of host proteins including the complement regulatory protein factor H (FH) and fibrinogen that plays a key role in coagulation. READ MORE

  5. 3. Mechanisms involved in macrophage phagocytosis of apoptotic cells

    Author : Anna Nilsson; Per-Arne Oldenborg; Karl-Eric Magnusson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; macrophages; dendritic cells; phagocytosis; apoptotic cells; senescent erythrocytes; CD47; SIRPalpha; LRP1; calreticulin; Immunology; Immunologi; immunologi; Immunology;

    Abstract : Efficient removal of apoptotic cells is critical for development, tissue remodelling, maintenance of homeostasis, and response to injury. Phagocytosis of apoptotic cells is mediated by many phagocytic receptors, soluble bridging molecules, and pro-phagocytic ligands on the surface of apoptotic cells. READ MORE

  6. 4. Quantifying Phagocytosis – studies on the antibody response during invasive streptococcal infections

    Author : Therese de Neergaard; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phagocytosis; Hill equation; Streptococcus pyogenes GAS ; Streptococcus dysgalactiae; Antibodies; invasive infection; Phagocytosis; Hill equation; Streptococcus pyogenes; Group A Streptococcus; Streptococcus dysgalactiae; Antibodies; Invasive infection;

    Abstract : The interaction between our immune system and pathogens encompasses a complex spectrum from symbiosis to potentially life-threatening diseases. Throughout evolution, our immune system has evolved numerous strategies such as phagocytosis to combat infections and protect us from diseases. READ MORE

  7. 5. Phagocytosis by neutrophils - studies on phagosome dynamics and membrane traffic modulation by Streptococcus pyogenes

    Author : Pontus Nordenfelt; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fluorescence microscopy; membrane traffic; neutrophil; Streptococcus pyogenes; phagosome; phagocytosis;

    Abstract : Neutrophils are our most numerous and deadly white blood cells and without them we would succumb quickly to infections by pathogens. The main mechanism that the neutrophils employ for our protection is phagocytosis, where they eat and enclose their target inside a membrane-bound organelle, the phagosome. READ MORE