Search for dissertations about: "phagosome"

Showing result 1 - 5 of 22 swedish dissertations containing the word phagosome.

  2. 1. Phagocytosis by neutrophils - studies on phagosome dynamics and membrane traffic modulation by Streptococcus pyogenes

    Author : Pontus Nordenfelt; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fluorescence microscopy; membrane traffic; neutrophil; Streptococcus pyogenes; phagosome; phagocytosis;

    Abstract : Neutrophils are our most numerous and deadly white blood cells and without them we would succumb quickly to infections by pathogens. The main mechanism that the neutrophils employ for our protection is phagocytosis, where they eat and enclose their target inside a membrane-bound organelle, the phagosome. READ MORE

  4. 2. Mechanisms of the intracellular survival of Francisella tularensis

    Author : Linda Tancred; Anders Sjöstedt; Jean Celli; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; Igl; MglA; J774; IFN-γ; RNS; ROS; phagosome; Clinical bacteriology; Klinisk bakteriologi; mikrobiologi; Microbiology;

    Abstract : Francisella tularensis is a gram-negative, highly virulent, intracellular bacterium which causes the zoonotic disease tularemia. The subspecies tularensis and holarctica are clinically important, and the former is the more virulent. The intracellular lifestyle of F. READ MORE

  5. 3. Reactive oxygen and nitrogen in host defence against Francisella tularensis

    Author : Helena Lindgren; Anders Sjöstedt; Tommy Sundquist; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Francisella tularensis; inducible nitric oxide synthase; phagocyte oxidase; macrophages; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; klinisk bakteriologi; Clinical Bacteriology;

    Abstract : Francisella tularensis, the causative agent of tularemia, is a potent human and animal pathogen. Initially upon infection of the host, intramacrophage proliferation of F. tularensis occurs but after activation of the acquired host immunity, the phagocytes become activated to kill the bacterium. In my thesis, I focused on mechanisms utilized by F. READ MORE

  6. 4. Characterization of the attenuated Francisella tularensis strain FSC043 : with special focus on the gene pdpC

    Author : Marie Lindgren; Anders Sjöstedt; Marina Santic; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; intracellular bacteria; J774; apoptosis; pyroptosis; PdpC; FSC043; Clinical Bacteriology; klinisk bakteriologi; mikrobiologi; Microbiology;

    Abstract : Francisella tularensis is a highly infective, intracellular bacterium. It is capable of infecting a wide range of mammals and causes the disease tularemia in humans. As a result of its high infectivity there have been a lot of efforts made to create a generally available vaccine against this pathogen. READ MORE

  7. 5. Regulation of phagocytosis and phagolysosome fusion in human leukocytes

    Author : Maria Lindmark; Per-Arne Oldenborg; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Professional phagocytes such as neutrophil granulocytes and macrophages are an esential part of the innate immune system. The neutrophils form the first line of defence against invading microorganisms and are important for rapid killing of the intruders. READ MORE