Search for dissertations about: "pharmaceutical coating"

Showing result 1 - 5 of 21 swedish dissertations containing the words pharmaceutical coating.

  2. 1. Particle Coating in a Wurster Type Bed

    Author : Stina Karlsson; Chalmers tekniska högskola; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Drying; Particle; Tracking technique; Spouted bed; Fluidisation; Multiphase flow; CFD; Trajectory; Coating; Wurster;

    Abstract : The Wurster bed process is frequently used for film coating. In the Wurster bed, particles circulate in the equipment and are sprayed with a liquid which forms a coating when dry. The procedure is repeated until the desired characteristics of the coating layer are obtained. READ MORE

  4. 2. Mass Transport through Phase Separated Films - Effects of Ethyl Cellulose Molecular Weight on Cellulose Derivative Blends for Pharmaceutical Coatings

    Author : Helene Andersson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Coating; Ethyl cellulose; Diffusion; Mass transport; Solvent evaporation; Molecular weight; Phase separation; Film; Hydroxypropyl cellulose; Polymer blend; Cellulose derivatives; Controlled release;

    Abstract : Polymer blends are utilized for a variety of applications, not least in pharmaceutical coatings for controlled release of drugs. For instance, blends of ethyl cellulose (EC) and the water-soluble hydroxypropyl cellulose (HPC) can be used to coat drug pellets for oral extendedrelease formulations. READ MORE

  5. 3. Spray-Dried Powders for Inhalation : Particle Formation and Formulation Concepts

    Author : Jessica Elversson; Göran Alderborn; Anna Millqvist-Fureby; Lars Hovgaard; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Spray drying; Particle formation; Density; Protein formulation; Encapsulation; Coating; Competitive adsorption; Polymer; ESCA; AFM; FTIR; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Abstract : Spray drying is a method with a high potential in the preparation of protein particles suitable for pulmonary delivery. However, surface induced denaturation of bio-molecules during atomization and subsequent drying can be substantial and it is therefore important to develop new formulation concept for concurrent encapsulation and stabilization of proteins during spray drying. READ MORE

  6. 4. Microgels as Carriers for Antimicrobial Peptides : Surface-bound microgels, and factors affecting peptide interactions

    Author : Lina Nyström; Martin Malmsten; Per Hansson; L. Andrew Lyon; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Antimicrobial peptides; Biomaterial coating; Drug delivery; Host defence peptides; Microgels; pH-responsive; Surface-bound; Pharmaceutical Physical Chemistry; Farmaceutisk fysikalisk kemi;

    Abstract : With a growing number of multi-resistant bacteria against conventional antibiotics, there is an urgent need to identify new antimicrobial therapeutics. One example that has gained considerable interest is antimicrobial peptides (AMPs). READ MORE

  7. 5. Preparation of Tablets from Reservoir Pellets with an Emphasis on the Compression Behaviour and Drug Release

    Author : Åsa Tunón; Göran Alderborn; Michael E. Aulton; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; multiple unit tablets; extrusion-spheronisation; barrier-coating; modified drug release; pellet types; compaction; tablet properties; deformation; densification; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

    Abstract : The preparation of multiple unit tablets was investigated in this thesis with the intention of gaining a deeper understanding of some of the factors that influence the properties of such tablets.Initially, three different types of pellets (drug, soft and disintegrant pellets) were combined as a model to investigate the ability of the mixture to form disintegrating tablets. READ MORE